Human LY6G6F Recombinant Protein (RPPB3892)

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SKU:
RPPB3892
Product type:
Recombinant Protein
Size:
20ug
Species:
Human
Target:
LY6G6F
Synonyms:
Lymphocyte Antigen 6 Complex Locus G6F
Synonyms:
Lymphocyte Antigen 6 Complex Locus G6D
Synonyms:
Chromosome 6 Open Reading Frame 21
Synonyms:
C6orf21
Source:
Escherichia Coli
Uniprot:
Q5SQ64
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Description

Product Name:Human LY6G6F Recombinant Protein
Product Code:RPPB3892
Size:20µg
Species:Human
Target:LY6G6F
Synonyms:Lymphocyte Antigen 6 Complex Locus G6F, Lymphocyte Antigen 6 Complex Locus G6D, Chromosome 6 Open Reading Frame 21, C6orf21, LY6G6D, NG32, G6F.
Source:Escherichia Coli
Physical Appearance:Sterile filtered colorless solution.
Formulation:The LY6G6F solution contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSADNMQAI YVALGEAVEL PCPSPPTLHG DEHLSWFCSP AAGSFTTLVA QVQVGRPAPD PGKPGRESRL RLLGNYSLWL EGSKEEDAGR YWCAVLGQHH NYQNWRVYDV LVLKGSQLSA RAADGSPCNV LLCSVVPSRR MDSVTWQEGK GPVRGRVQSF WGSEAALLLV CPGEGLSEPR SRRPRIIRCL MTHNKGVSFS LAASIDASPA LCAPSTGWDM PW

The human Lymphocyte Antigen 6 Complex Locus G6F (LY6G6F) protein is a type I transmembrane protein belonging to the immunoglobin (Ig) superfamily, which contains cell-surface proteins involved in the immune system and cellular recognition. The LY6G6F protein has a role in the downstream signal transduction pathways involving GRB2 and GRB7.

LY6G6F Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 242 amino acids (17-235) and having a molecular mass of 26.2kDa.LY6G6F is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:G6f: a cell-surface protein encoded in the class III region of the human major histocompatibility complex. Belongs to the immunoglobulin superfamily. Tyrosine phosphorylation induces interactions with the SH2 domanis of Grb2 and Grb7. Appears to be coupled with downstream signal transduction pathways involving Grb2 and Grb7, including the Ras-MAP kinase pathway.
UniProt Protein Details:

Protein type:Cell surface; Membrane protein, integral

Chromosomal Location of Human Ortholog: 6p21

NCBI Summary:The human G6f protein is a type I transmembrane protein belonging to the immunoglobin (Ig) superfamily, which is comprised of cell-surface proteins involved in the immune system and cellular recognition (de Vet et al., 2003 [PubMed 12852788]).[supplied by OMIM, Mar 2008]
UniProt Code:Q5SQ64
NCBI GenInfo Identifier:172045922
NCBI Gene ID:259215
NCBI Accession:Q5SQ64.2
UniProt Secondary Accession:Q5SQ64,O95869, Q7Z5H2, Q96QC7, Q9NZJ1, B0UXB7,
UniProt Related Accession:Q5SQ64
Molecular Weight:40,892 Da
NCBI Full Name:Lymphocyte antigen 6 complex locus protein G6f
NCBI Synonym Full Names:lymphocyte antigen 6 complex, locus G6F
NCBI Official Symbol:LY6G6F  
NCBI Official Synonym Symbols:G6f; NG32; LY6G6D; C6orf21  
NCBI Protein Information:lymphocyte antigen 6 complex locus protein G6f
UniProt Protein Name:Lymphocyte antigen 6 complex locus protein G6f
Protein Family:Lymphocyte antigen 6 complex locus protein
UniProt Gene Name:LY6G6F  
UniProt Entry Name:LY66F_HUMAN
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