Human KCTD4 Recombinant Protein (RPPB3777)

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SKU:
RPPB3777
Product type:
Recombinant Protein
Size:
10ug
Species:
Human
Target:
KCTD4
Synonyms:
Potassium Channel Tetramerization Domain Containing 4
Synonyms:
PotassiumChannel Tetramerisation Domain Containing 4
Synonyms:
bA321C243
Synonyms:
BTB/POZDomain-Containing Protein KCTD4
Source:
Escherichia Coli
Uniprot:
Q8WVF5
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Description

Product Name:Human KCTD4 Recombinant Protein
Product Code:RPPB3777
Size:10µg
Species:Human
Target:KCTD4
Synonyms:Potassium Channel Tetramerization Domain Containing 4, PotassiumChannel Tetramerisation Domain Containing 4, bA321C24.3, BTB/POZDomain-Containing Protein KCTD4.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:KCTD4 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 40%glycerol and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
Purity:Greaterthan 85% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMERKINR REKEKEYEGK HNSLEDTDQG KNCKSTLMTL NVGGYLYITQKQTLTKYPDT FLEGIVNGKI LCPFDADGHY FIDRDGLLFR HVLNFLRNGE LLLPEGFREN QLLAQEAEFFQLKGLAEEVK SRWEKEQLTP RETTFLEITD NHDRSQGLRI FCNAPDFISK IKSRIVLVSK SRLDGFPEEF SISSNIIQFK YFIKSENGTRLVLKEDNTFV CTLETLKFEA IMMALKCGFR LLTSLDCSKG SIVHSDALHF IK

KCTD4also known as Potassium Channel Tetramerisation Domain Containing 4 has an N-terminalhomodimerization domain which contains multiple copies of kelch repeats and C2H2-typezinc fingers. Proteins which include BTB domains are consider being involved intranscriptional regulation through control of chromatin structure and function.In addition, KCTD4 is a 259 amino acid protein which contains one BTB domain, apossible role as a transcriptional regulator may be suggested.

KCTD4 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 282 amino acids (1-259 a.a) and having a molecular mass of 32.4kDa.KCTD4 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:KCTD4: Chromosomal Location of Human Ortholog: 13q14.12Biological Process: protein homooligomerization
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q8WVF5
NCBI GenInfo Identifier:146198864
NCBI Gene ID:386618
NCBI Accession:NP_940686.2
UniProt Secondary Accession:Q8WVF5,Q5W0P9
UniProt Related Accession:Q8WVF5
Molecular Weight:
NCBI Full Name:BTB/POZ domain-containing protein KCTD4
NCBI Synonym Full Names:potassium channel tetramerization domain containing 4
NCBI Official Symbol:KCTD4  
NCBI Official Synonym Symbols:bA321C24.3  
NCBI Protein Information:BTB/POZ domain-containing protein KCTD4
UniProt Protein Name:BTB/POZ domain-containing protein KCTD4
UniProt Synonym Protein Names:
Protein Family:BTB/POZ domain-containing protein
UniProt Gene Name:KCTD4  
UniProt Entry Name:KCTD4_HUMAN
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