The Human IL-6 Monoclonal Antibody PE Conjugated (MQ2-13A5) (AGEL2068) offered by Assay Genie is a valuable tool for researchers studying the role of Interleukin-6 (IL-6) in immune responses and inflammatory processes. This antibody is specifically designed to target IL-6, a key cytokine involved in a wide range of physiological and pathological processes, including inflammation, immune response, and hematopoiesis.With its PE conjugation, this monoclonal antibody is optimized for flow cytometry applications, allowing for the precise detection and quantification of IL-6 in various cell types and experimental settings. The high specificity and sensitivity of the antibody ensure reliable and accurate results, making it an essential reagent for immunology and cytokine research.IL-6 is known for its diverse functions in both health and disease, playing a crucial role in the regulation of immune responses, acute-phase reactions, and chronic inflammation.
Dysregulation of IL-6 signaling has been implicated in various conditions, including autoimmune diseases, cancer, and inflammatory disorders. By using the Human IL-6 Monoclonal Antibody PE Conjugated (MQ2-13A5), researchers can gain valuable insights into the mechanisms underlying these diseases and develop potential therapeutic strategies targeting IL-6.Overall, this antibody provides a powerful tool for studying the complex roles of IL-6 in immune regulation and inflammatory pathways, offering researchers the ability to unravel the intricate interplay between cytokines and immune cells in health and disease.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P05231
Gene ID:
3569
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
IL-6 is a potent lymphoid cell growth factor that stimulates the growth and survival of certain B cells and T cells. IL-6 plays a role in host defense, acute phase reactions, immune response, and hematopoiesis. IL-6 is expressed by T cells, B cells, monocytes, fibroblasts, hepatocytes, endothelial cells, and keratinocytes.