The Human IL-4 Monoclonal Antibody FITC Conjugated (MP4-25D2) is a cutting-edge tool for researchers delving into the realm of human interleukin-4 (IL-4), a pivotal cytokine involved in immune responses. This monoclonal antibody, conjugated with FITC for easy visualization, has been meticulously developed to exhibit high specificity and reactivity with human IL-4 protein.IL-4 is a key player in the regulation of immune responses, particularly in the context of allergic reactions and inflammation. By targeting IL-4, researchers can gain valuable insights into immune modulation and its implications in diseases such as asthma, allergies, and autoimmune disorders.
This antibody is an essential component for studies exploring the intricate mechanisms of IL-4 signaling and its potential as a therapeutic target.With its ability to precisely bind to IL-4, this monoclonal antibody opens up new avenues for investigating the role of IL-4 in various cell types and biological processes. Ideal for applications such as flow cytometry and immunofluorescence, this antibody empowers researchers in immunology, cell biology, and pharmacology to deepen their understanding of IL-4 function and its relevance in health and disease.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P05112
Gene ID:
3565
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
IL-4 is a pleiotropic cytokine that is produced by activated T cells, mast cells, and basophils. IL-4 elicits many different biological responses but has two dominant functions. The first is regulating differentiation of naïve CD4+ T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10, and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells.