Human HSPB6 Recombinant Protein (RPPB5254)

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SKU:
RPPB5254
Product type:
Recombinant Protein
Size:
10ug
Species:
Human
Target:
HSPB6
Synonyms:
HeatShock Protein
Synonyms:
Alpha-Crystallin-Related
Synonyms:
B6
Synonyms:
Heat Shock 20 KDa-Like Protein P20
Source:
Escherichia Coli
Uniprot:
O14558
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Description

Product Name:Human HSPB6 Recombinant Protein
Product Code:RPPB5254
Size:10µg
Species:Human
Target:HSPB6
Synonyms:HeatShock Protein, Alpha-Crystallin-Related, B6, Heat Shock 20 KDa-Like Protein P20,Hsp20, Protein Phosphatase 1, Regulatory Subunit 91, Epididymis Luminal Protein55, Heat Shock Protein Beta-6, Protein Phosphatase 1, Regulatory Subunit 91, PPP1R91,HEL55, HspB6, Heat shock protein beta-6.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:HSPB6 protein solution (0.25mg/ml) containing Phosphatebuffered saline (pH7.4), 30% glycerol, 1mM DTT, 1mM EDTA and 0.1mM PMSF.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 95.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSHMEIPVP VQPSWLRRAS APLPGLSAPG RLFDQRFGEG LLEAELAALCPTTLAPYYLR APSVALPVAQ VPTDPGHFSV LLDVKHFSPE EIAVKVVGEH VEVHARHEER PDEHGFVAREFHRRYRLPPG VDPAAVTSAL SPEGVLSIQA APASAQAPPP AAAK

Heat shock prtein beta-6, also known as HSPB6 is a member of the smallheat shock protein (HSP20) family.  Thislocus encodes a heat shock protein.  HSPB6plays a role in smooth muscle relaxation. Among the diseases which are associatedwith HSPB6: Cerebral hemorrhage and Cerebral amyloid angiopathy.

HSPB6 Human Recombinant produced in E.Coli is a single, non-glycosylatedpolypeptide chain containing 184 amino acids (1-160 a.a) and having a molecularmass of 19.7kDa.HSPB6 is fused to a 24amino acid His-tag at N-terminus & purified by proprietary chromatographictechniques.

UniProt Protein Function:HSP20: a small heat shock protein of the HSP20 family.
UniProt Protein Details:

Protein type:Heat shock protein; Chaperone

Chromosomal Location of Human Ortholog: 19q13.12

Cellular Component: cytoplasm; nucleus

Molecular Function:protein binding; protein homodimerization activity

NCBI Summary:This locus encodes a heat shock protein. The encoded protein likely plays a role in smooth muscle relaxation. [provided by RefSeq, Jan 2012]
UniProt Code:O14558
NCBI GenInfo Identifier:22096351
NCBI Gene ID:126393
NCBI Accession:O14558.2
UniProt Secondary Accession:O14558,O14551, Q6NVI3, Q96MG9,
UniProt Related Accession:O14558
Molecular Weight:17,136 Da
NCBI Full Name:Heat shock protein beta-6
NCBI Synonym Full Names:heat shock protein family B (small) member 6
NCBI Official Symbol:HSPB6  
NCBI Official Synonym Symbols:HEL55; Hsp20; PPP1R91  
NCBI Protein Information:heat shock protein beta-6
UniProt Protein Name:Heat shock protein beta-6
UniProt Synonym Protein Names:Heat shock 20 kDa-like protein p20
Protein Family:Heat shock protein
UniProt Gene Name:HSPB6  
UniProt Entry Name:HSPB6_HUMAN
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