Human HSPB6 Recombinant Protein (RPPB5254)
- SKU:
- RPPB5254
- Product type:
- Recombinant Protein
- Size:
- 10ug
- Species:
- Human
- Target:
- HSPB6
- Synonyms:
- HeatShock Protein
- Alpha-Crystallin-Related
- B6
- Heat Shock 20 KDa-Like Protein P20
- Source:
- Escherichia Coli
- Uniprot:
- O14558
Description
| Product Name: | Human HSPB6 Recombinant Protein |
| Product Code: | RPPB5254 |
| Size: | 10µg |
| Species: | Human |
| Target: | HSPB6 |
| Synonyms: | HeatShock Protein, Alpha-Crystallin-Related, B6, Heat Shock 20 KDa-Like Protein P20,Hsp20, Protein Phosphatase 1, Regulatory Subunit 91, Epididymis Luminal Protein55, Heat Shock Protein Beta-6, Protein Phosphatase 1, Regulatory Subunit 91, PPP1R91,HEL55, HspB6, Heat shock protein beta-6. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | HSPB6 protein solution (0.25mg/ml) containing Phosphatebuffered saline (pH7.4), 30% glycerol, 1mM DTT, 1mM EDTA and 0.1mM PMSF. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMEIPVP VQPSWLRRAS APLPGLSAPG RLFDQRFGEG LLEAELAALCPTTLAPYYLR APSVALPVAQ VPTDPGHFSV LLDVKHFSPE EIAVKVVGEH VEVHARHEER PDEHGFVAREFHRRYRLPPG VDPAAVTSAL SPEGVLSIQA APASAQAPPP AAAK |
Heat shock prtein beta-6, also known as HSPB6 is a member of the smallheat shock protein (HSP20) family. Thislocus encodes a heat shock protein. HSPB6plays a role in smooth muscle relaxation. Among the diseases which are associatedwith HSPB6: Cerebral hemorrhage and Cerebral amyloid angiopathy.
HSPB6 Human Recombinant produced in E.Coli is a single, non-glycosylatedpolypeptide chain containing 184 amino acids (1-160 a.a) and having a molecularmass of 19.7kDa.HSPB6 is fused to a 24amino acid His-tag at N-terminus & purified by proprietary chromatographictechniques.
| UniProt Protein Function: | HSP20: a small heat shock protein of the HSP20 family. |
| UniProt Protein Details: | Protein type:Heat shock protein; Chaperone Chromosomal Location of Human Ortholog: 19q13.12 Cellular Component: cytoplasm; nucleus Molecular Function:protein binding; protein homodimerization activity |
| NCBI Summary: | This locus encodes a heat shock protein. The encoded protein likely plays a role in smooth muscle relaxation. [provided by RefSeq, Jan 2012] |
| UniProt Code: | O14558 |
| NCBI GenInfo Identifier: | 22096351 |
| NCBI Gene ID: | 126393 |
| NCBI Accession: | O14558.2 |
| UniProt Secondary Accession: | O14558,O14551, Q6NVI3, Q96MG9, |
| UniProt Related Accession: | O14558 |
| Molecular Weight: | 17,136 Da |
| NCBI Full Name: | Heat shock protein beta-6 |
| NCBI Synonym Full Names: | heat shock protein family B (small) member 6 |
| NCBI Official Symbol: | HSPB6 |
| NCBI Official Synonym Symbols: | HEL55; Hsp20; PPP1R91 |
| NCBI Protein Information: | heat shock protein beta-6 |
| UniProt Protein Name: | Heat shock protein beta-6 |
| UniProt Synonym Protein Names: | Heat shock 20 kDa-like protein p20 |
| Protein Family: | Heat shock protein |
| UniProt Gene Name: | HSPB6 |
| UniProt Entry Name: | HSPB6_HUMAN |
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