Human Gankyrin/PSDM10 Recombinant Protein (RPES4761)

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SKU:
RPES4761
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
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Description

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Human Gankyrin/PSDM10 Recombinant Protein

Gankyrin is a multicatalytic proteinase oncoprotein consists of 7 ankyrin repeats. Gankyrin overexpressed in most hepatocellular carcinomas. Gankyrin is involved in theregulation of the phosphorylation of the retinoblastoma protein by CDK4 to enhance the ubiquitinylation of p53 by MDM2. Gankyrin is also involved in progression of esophageal squamous cell carcinoma. Gankyrin plays an oncogenic role especially in early stages of human epatocarcinogenesis.

Product Name:Human Gankyrin/PSDM10 Recombinant Protein (RPES4761)
Product Code:RPES4761
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:26S Proteasome Non-ATPase Regulatory Subunit 10, 26S Proteasome Regulatory Subunit p28, Gankyrin, p28(GANK), PSMD10
Accession:O75832
Sequence:Met 1-Gly226
Fusion tag:
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Gankyrin is produced by our E.coli expression system and the target gene encoding Met1-Gly226 is expressed.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:24.4 kDa
AP Mol Mass:26 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, 10% Glycerol, pH 7.4.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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