Human EIF1 Recombinant Protein (RPPB3419)

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SKU:
RPPB3419
Product type:
Recombinant Protein
Size:
10ug
Species:
Human
Target:
EIF1
Synonyms:
A121
Synonyms:
EIF-1
Synonyms:
EIF1A
Synonyms:
ISO1
Source:
Escherichia Coli
Uniprot:
P41567
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Description

Product Name:Human EIF1 Recombinant Protein
Product Code:RPPB3419
Size:10µg
Species:Human
Target:EIF1
Synonyms:A121, EIF-1, EIF1A, ISO1, SUI1, Eukaryotic translation initiation factor 1, eIF1, Protein translation factor SUI1 homolog, Sui1iso1, EIF1.
Source:Escherichia Coli
Physical Appearance:Sterile filtered colorless solution.
Formulation:The EIF1 protein solution contains 20mM Tris-HCl, pH-8, 100mM NaCl, 1mM DTT and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWAGSMSA IQNLHSFDPF ADASKGDDLL PAGTEDYIHI RIQQRNGRKT LTTVQGIADD YDKKKLVKAF KKKFACNGTV IEHPEYGEVI QLQGDQRKNI CQFLVEIGLA KDDQLKVHGF

EIF1 is important for scanning and plays a role in initiation site selection. EIF1 promotes the assembly of 48S ribosomal at the authentic initiation codon of a conventional capped mRNA.

EIF1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 150 amino acids (1-113 a.a.) and having a molecular weight of 16.9kDa.The EIF1 is fused to 37 a.a. His-Tag at N-terminus and purified by proprietary chromatographic techniques.

UniProt Protein Function:EIF1: a translation initiation factor. Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA.
UniProt Protein Details:

Protein type:Translation; Translation initiation

Chromosomal Location of Human Ortholog: 17q21.2

Cellular Component: cytoplasm; nucleus

Molecular Function:RNA binding; translation factor activity, nucleic acid binding

Biological Process: regulation of translational initiation

UniProt Code:P41567
NCBI GenInfo Identifier:1174483
NCBI Gene ID:10209
NCBI Accession:P41567.1
UniProt Secondary Accession:P41567,Q9UNQ9,
UniProt Related Accession:P41567
Molecular Weight:13kDa
NCBI Full Name:Eukaryotic translation initiation factor 1
NCBI Synonym Full Names:eukaryotic translation initiation factor 1
NCBI Official Symbol:EIF1  
NCBI Official Synonym Symbols:A121; ISO1; SUI1; EIF-1; EIF1A  
NCBI Protein Information:eukaryotic translation initiation factor 1
UniProt Protein Name:Eukaryotic translation initiation factor 1
UniProt Synonym Protein Names:A121; Protein translation factor SUI1 homolog; Sui1iso1
Protein Family:Eukaryotic translation initiation factor
UniProt Gene Name:EIF1  
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