Human EEF1G Recombinant Protein (RPPB3398)

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SKU:
RPPB3398
Product type:
Recombinant Protein
Size:
20ug
Species:
Human
Target:
EEF1G
Synonyms:
EF1G
Synonyms:
GIG35
Synonyms:
Elongation factor 1-gamma
Synonyms:
Eukaryotic Translation Elongation Factor 1 Gamma
Source:
Escherichia Coli
Uniprot:
P26641
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Description

Product Name:Human EEF1G Recombinant Protein
Product Code:RPPB3398
Size:20µg
Species:Human
Target:EEF1G
Synonyms:EF1G, GIG35, Elongation factor 1-gamma, Eukaryotic Translation Elongation Factor 1 Gamma, EEF1G, EF-1-gamma, eEF-1B gamma, PRO1608.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The EEF1G solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMAAGTLY TYPENWRAFK ALIAAQYSGA QVRVLSAPPH FHFGQTNRTP EFLRKFPAGK VPAFEGDDGF CVFESNAIAY YVSNEELRGS TPEAAAQVVQ WVSFADSDIV PPASTWVFPT LGIMHHNKQA TENAKEEVRR ILGLLDAYLK TRTFLVGERV TLADITVVCT LLWLYKQVLE PSFRQAFPNT NRWFLTCINQ PQFRAVLGEV KLCEKMAQFD AKKFAETQPK KDTPRKEKGS REEKQKPQAE RKEEKKAAAP APEEEMDECE QALAAEPKAK DPFAHLPKST FVLDEFKRKY SNEDTLSVAL PYFWEHFDKD GWSLWYSEYR FPEELTQTFM SCNLITGMFQ RLDKLRKNAF ASVILFGTNN SSSISGVWVF RGQELAFPLS PDWQVDYESY TWRKLDPGSE ETQTLVREYF SWEGAFQHVG KAFNQGKIFK

Eukaryotic Translation Elongation Factor 1 Gamma (EEF1G) takes part in anchoring the complex to additional cellular components. EEF1G is a multi-protein complex which is in charge of the delivery of aminoacyl-tRNAs to the ribosome. Over expression of EEF1G is linked with pancreatic cancer, due to the role of EEF1G protein in the oncogenic transformation process.

EEF1G Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 460 amino acids (1-437) and having a molecular mass of 52.5 kDa.EEF1G is fused to a 23 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.

UniProt Protein Function:EEF1G: Probably plays a role in anchoring the complex to other cellular components.
UniProt Protein Details:

Protein type:Translation; Translation elongation

Chromosomal Location of Human Ortholog: 11q12.3

Cellular Component: cytoplasm; cytosol; endoplasmic reticulum; membrane; nucleus

Molecular Function:cadherin binding; protein binding

Biological Process: response to virus; translational elongation

NCBI Summary:This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit contains an N-terminal glutathione transferase domain, which may be involved in regulating the assembly of multisubunit complexes containing this elongation factor and aminoacyl-tRNA synthetases. [provided by RefSeq, Jul 2008]
UniProt Code:P26641
NCBI GenInfo Identifier:119165
NCBI Gene ID:1937
NCBI Accession:P26641.3
UniProt Secondary Accession:P26641,Q6PJ62, Q6PK31, Q96CU2, Q9P196, B4DTG2,
UniProt Related Accession:P26641
Molecular Weight:50kDa
NCBI Full Name:Elongation factor 1-gamma
NCBI Synonym Full Names:eukaryotic translation elongation factor 1 gamma
NCBI Official Symbol:EEF1G  
NCBI Official Synonym Symbols:EF1G; GIG35  
NCBI Protein Information:elongation factor 1-gamma
UniProt Protein Name:Elongation factor 1-gamma
UniProt Synonym Protein Names:eEF-1B gamma
Protein Family:Elongation factor
UniProt Gene Name:EEF1G  
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