Human CMC1 Recombinant Protein (RPPB3211)

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SKU:
RPPB3211
Product type:
Recombinant Protein
Size:
20ug
Species:
Human
Target:
CMC1
Synonyms:
C3orf68
Synonyms:
Cmc1p
Synonyms:
COX assembly mitochondrial protein homolog
Source:
Escherichia Coli
Uniprot:
Q7Z7K0
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Description

Product Name:Human CMC1 Recombinant Protein
Product Code:RPPB3211
Size:20µg
Species:Human
Target:CMC1
Synonyms:C3orf68, Cmc1p, COX assembly mitochondrial protein homolog.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:CMC1 protein solution (0.5mg/ml) contains 20mM Tris-HCl buffer, (pH 8.0), 0.4M UREA and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 85.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMALDPAD QHLRHVEKDV LIPKIMREKA KERCSEQVQD FTKCCKNSGV LMVVKCRKEN SALKECLTAY YNDPAFYEEC KMEYLKEREE FRKTGIPTKK RLQKLPTSM

COX Assembly Mitochondrial Protein 1(CMC1) is a member of the CMC family. CMC1 is required for mitochondrial cytochrome c oxidase (COX) assembly and respiration. CMC1 attaches copper and might be involved in copper trafficking and distribution to COX and SOD1.

CMC1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 129 amino acids (1-106 a.a.) and having a molecular mass of 14.9kDa.CMC1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:CMC1: Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration. Binds copper. May be involved in copper trafficking and distribution to COX and SOD1. Belongs to the CMC family.Chromosomal Location of Human Ortholog: 3p24.1Cellular Component: mitochondrion
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q7Z7K0
NCBI GenInfo Identifier:30851665
NCBI Gene ID:152100
NCBI Accession:BC052644
UniProt Secondary Accession:Q7Z7K0,Q68DJ7
UniProt Related Accession:Q7Z7K0
Molecular Weight:12,490 Da
NCBI Full Name:Homo sapiens COX assembly mitochondrial protein homolog (S. cerevisiae), mRNA
NCBI Synonym Full Names:C-X9-C motif containing 1
NCBI Official Symbol:CMC1  
NCBI Official Synonym Symbols:C3orf68  
NCBI Protein Information:COX assembly mitochondrial protein homolog
UniProt Protein Name:COX assembly mitochondrial protein homolog
UniProt Synonym Protein Names:
Protein Family:COX assembly mitochondrial protein
UniProt Gene Name:CMC1  
UniProt Entry Name:COXM1_HUMAN
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