Human CHAC2 Recombinant Protein (RPPB3163)

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SKU:
RPPB3163
Product type:
Recombinant Protein
Size:
10ug
Species:
Human
Target:
CHAC2
Synonyms:
ChaC Cation Transport Regulator Homolog 2 (E Coli)
Synonyms:
ChaC Cation Transport Regulator-Like 2 (E Coli)
Synonyms:
Gamma-GCT Acting On Glutathione Homolog 2
Source:
Escherichia Coli
Uniprot:
Q8WUX2
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Description

Product Name:Human CHAC2 Recombinant Protein
Product Code:RPPB3163
Size:10µg
Species:Human
Target:CHAC2
Synonyms:ChaC Cation Transport Regulator Homolog 2 (E. Coli), ChaC Cation Transport Regulator-Like 2 (E. Coli), Gamma-GCT Acting On Glutathione Homolog 2.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:The CHAC2 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 100mM NaCl and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMWVFGYG SLIWKVDFPY QDKLVGYITN YSRRFWQGST DHRGVPGKPG RVVTLVEDPA GCVWGVAYRL PVGKEEEVKA YLDFREKGGY RTTTVIFYPK DPTTKPFSVL LYIGTCDNPD YLGPAPLEDI AEQIFNAAGP SGRNTEYLFE LANSIRNLVP EEADEHLFAL EKLVKERLEG KQNLNCI

Cation transport regulator-like protein 2 (CHAC2) is a member of the chaC family. Catalyzes the cleavage glutathione into 5-oxoproline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

CHAC2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 207 amino acids (1-184) and having a molecular mass of 23.3 kDa. CHAC2 is fused to a 23 amino acid His-tag at N-terminus.

UniProt Protein Function:CHAC2: Belongs to the chaC family.Chromosomal Location of Human Ortholog: 2p16Cellular Component: cytosolMolecular Function: gamma-glutamylcyclotransferase activityBiological Process: glutathione biosynthetic process
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q8WUX2
NCBI GenInfo Identifier:74730779
NCBI Gene ID:494143
NCBI Accession:Q8WUX2.1
UniProt Secondary Accession:Q8WUX2,Q8WVI8
UniProt Related Accession:Q8WUX2
Molecular Weight:20,875 Da
NCBI Full Name:Putative glutathione-specific gamma-glutamylcyclotransferase 2
NCBI Synonym Full Names:ChaC cation transport regulator homolog 2
NCBI Official Symbol:CHAC2  
NCBI Official Synonym Symbols:
NCBI Protein Information:putative glutathione-specific gamma-glutamylcyclotransferase 2
UniProt Protein Name:Putative glutathione-specific gamma-glutamylcyclotransferase 2
UniProt Synonym Protein Names:Cation transport regulator-like protein 2
Protein Family:
UniProt Gene Name:CHAC2  
UniProt Entry Name:CHAC2_HUMAN
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