The Human CD90 Monoclonal Antibody (PE/Cyanine5.5 Conjugated 5E10, AGEL1833) is a specialized antibody designed for researchers studying CD90, a cell surface marker commonly used to identify and isolate specific cell populations. This monoclonal antibody, labeled with PE/Cyanine5.5, offers high specificity and sensitivity for human samples, enabling accurate detection and analysis in flow cytometry and other fluorescence-based applications.CD90, also known as Thy-1, is a key marker for various cell types, including stem cells, fibroblasts, and certain immune cells. Its expression pattern and functional roles in cell signaling and differentiation make it a vital player in developmental biology, regenerative medicine, and cancer research.
By targeting CD90 with this monoclonal antibody, researchers can explore its functions, interactions, and potential therapeutic implications in a variety of experimental settings.The PE/Cyanine5.5 conjugation enhances the utility of this antibody for multicolor flow cytometry experiments, allowing for simultaneous detection of CD90 along with other markers of interest. Its compatibility with diverse research applications and its reliable performance with human samples make this antibody a valuable tool for investigating the biology of CD90-expressing cells and their involvement in various physiological and pathological processes.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P04216
Gene ID:
7070
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD90 is a 25-35 kD GPI-anchored protein, also known as Thy-1. It belongs to the Ig superfamily. Human CD90 is expressed on neuronal cells, a subset of CD34+ cells, a subset of fetal liver cells and fetal thymocytes, fibroblasts, activated endothelial cells, and some leukemia cell lines. CD34+CD90+ cells are primitive hematopoietic stem cells. It has been reported that Thy-1 binds with β2 and β3 integrins and plays bimodal roles in the regulation of cell adhesion and neurite outgrowth, and inhibits hematopoietic stem cells proliferation and differentiation.