FITC Anti-Human CD8a Antibody [OKT-8] (AGEL0407)

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SKU:
AGEL0407
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a
Clone:
OKT-8
Conjugation:
FITC
Applications:
FC
Frequently bought together:

Description

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FITC Anti-Human CD8a Antibody [OKT-8]

The Human CD8A Monoclonal Antibody (FITC Conjugated) - OKT-8 (AGEL0407) from AssayGenie is a cutting-edge reagent designed for precise research applications involving CD8A, a critical cell surface marker involved in immune responses. This monoclonal antibody, labeled with FITC for fluorescent detection, is specifically engineered for high reactivity with human samples, ensuring accurate and reliable results in various assays.CD8A, a core component of the CD8 T-cell co-receptor, is essential for the function and regulation of cytotoxic T cells in the immune system. By targeting CD8A with this specialized antibody, researchers gain a powerful tool for the detection and analysis of CD8A-expressing cells in diverse experimental settings. This makes it particularly suitable for immunology studies, cancer research, and immunotherapy development.

The OKT-8 monoclonal antibody recognizes the CD8A protein with exceptional specificity, enabling researchers to investigate the role of CD8 T cells in immune responses, viral infections, autoimmune diseases, and tumor immunity. Its fluorescent conjugation not only facilitates visualization and quantification of CD8A-positive cells in flow cytometry and immunofluorescence assays but also enhances the sensitivity and precision of experimental results.By utilizing the Human CD8A Monoclonal Antibody (FITC Conjugated) - OKT-8 (AGEL0407) from AssayGenie, scientists can delve deeper into the intricate mechanisms of immune regulation and host defense, paving the way for innovative discoveries and therapeutic advancements in the fields of immunology and oncology.

Product Title:FITC Anti-Human CD8a Antibody [OKT-8]
SKU:AGEL0407
Size:20 Tests, 100 Tests, 200 Tests
Clone No:OKT-8
Synonyms:T-cell surface glycoprotein CD8 alpha chain;CD8A;T-lymphocyte differentiation antigen T8/Leu-2;MAL;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:FITC Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P01732
Gene ID:925
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.

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