The Human CD69 Monoclonal Antibody (PE/Cyanine7 Conjugated, FN50) is a cutting-edge tool designed for researchers studying CD69, a key cell surface marker involved in immune cell activation and migration. This monoclonal antibody, derived from mouse hybridoma technology, exhibits high specificity and sensitivity towards human CD69, making it a reliable choice for flow cytometry and other immunological assays.CD69, also known as very early activation antigen, is a critical modulator of immune responses, playing a pivotal role in the early stages of immune activation and inflammation. Its expression on various immune cell types serves as a reliable marker for their activation status, making it an invaluable target for investigating immune dynamics in health and disease states. By utilizing the CD69 Monoclonal Antibody, researchers can gain valuable insights into immune cell behavior, aiding in the understanding of various immune-related processes such as infection, inflammation, and autoimmune disorders.
This cutting-edge antibody opens up new possibilities for exploring the intricate mechanisms underlying immune cell activation and modulation. Its conjugation with PE/Cyanine7 enables versatile applications in flow cytometry, allowing for precise identification and analysis of CD69-expressing cells within complex biological samples. Researchers in immunology, oncology, and infectious disease fields can leverage the capabilities of this antibody to deepen their understanding of immune responses and potentially uncover novel therapeutic targets for a range of immune-related conditions.
Product Title:
PE/Cyanine7 Anti-Human CD69 Antibody [FN50]
SKU:
AGEL1691
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
FN50
Synonyms:
Early activation antigen CD69;Activation inducer molecule;AIM;EA1;MLR-3;
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
Q07108
Gene ID:
969
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD69 is a 27-33 kD type II transmembrane protein also known as activation inducer molecule (AIM), very early activation antigen (VEA), and MLR3. It is a member of the C-type lectin family, expressed as a disulfide-linked homodimer. Other members of this receptor family include NKG2, NKR-P1 CD94, and Ly49. CD69 is transiently expressed on activated leukocytes including T cells, thymocytes, B cells, NK cells, neutrophils, and eosinophils. CD69 is constitutively expressed by a subset of medullary mature thymocytes, platelets, mantle B cells, and certain CD4+ T cells in germinal centers of normal lymph nodes. CD69 is involved in early events of lymphocyte, monocyte, and platelet activation, and has a functional role in redirected lysis mediated by activated NK cells.