The Human CD64 Monoclonal Antibody PE/Cyanine5.5 Conjugated (AGEL1118) offered by Assay Genie is a powerful tool for researchers studying the CD64 protein, an important cell surface receptor involved in immune responses. This antibody, conjugated with PE/Cyanine5.5, is specifically designed for flow cytometry applications, allowing for accurate detection and analysis of CD64 expression in human samples.CD64, also known as FcγRI, plays a key role in the immune system by mediating the uptake of immune complexes and triggering immune responses. Its expression levels have been linked to various disease states, including autoimmune disorders and infectious diseases.
By using this monoclonal antibody, researchers can gain insights into the functions of CD64 in different cell types, aiding in the study of immune regulation and potential therapeutic interventions.The AGEL1118 antibody from Assay Genie is rigorously validated for its specificity and sensitivity, ensuring reliable results in research applications. With its ability to target CD64 with precision, this antibody is a valuable tool for advancing our understanding of immune responses and developing targeted therapies for immune-related disorders.
Product Title:
PE/Cyanine5.5 Anti-Human CD64 Antibody [10.1]
SKU:
AGEL1118
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
10.1
Synonyms:
Fc fragment of IgG high affinity Ia/b/c receptor;CD64A/B/C;CD64;Fc gamma RI;FCGR1A/B/C;IGFR 1;
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P12314
Gene ID:
2209
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).