The Human CD5 Monoclonal Antibody (Biotin Conjugated) (AG-EL0187) offered by Assay Genie is a cutting-edge research tool designed for the detection and analysis of CD5, a key cell surface marker involved in immune function. This high-quality antibody, developed for use in various research applications, including flow cytometry and immunohistochemistry, exhibits exceptional reactivity specifically with human samples.CD5, also known as Leu-1, is a crucial protein expressed on T cells and B-1a cells, playing a significant role in regulating immune responses and promoting cell signaling. The precise binding of this monoclonal antibody to CD5 allows for accurate identification and characterization of CD5-expressing cells in diverse biological contexts.
This makes it an indispensable tool for investigations in immunology, oncology, and autoimmune diseases.By understanding the intricate mechanisms of CD5 function and its impact on immune regulation, researchers can gain valuable insights into the development of targeted therapies for conditions such as cancer, autoimmune disorders, and inflammatory diseases. The Human CD5 Monoclonal Antibody (Biotin Conjugated) from Assay Genie empowers scientists with the precision and reliability needed to advance research in these critical areas of study.
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
P06127
Gene ID:
921
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD5 is a 67 kD single chain type I glycoprotein also known as Leu-1, Ly-1 and T1. It is a member of the scavenger receptor superfamily found on T cells, thymocytes, B cell subsets, chronic B lymphocytic leukemia (B-Cells), and peripheral blood dendritic cells. CD5 modulates T and B cell receptor signaling, thymocyte maturation, and T-B cell interactions upon binding to ligands such as CD72.