The Human CD44 Monoclonal Antibody PerCP-Cyanine5.5 Conjugated (P2A1) is a specialized tool for researchers working with CD44, a multifunctional cell surface glycoprotein involved in cell adhesion, migration, and signaling. This monoclonal antibody, conjugated with PerCP-Cyanine5.5, offers high specificity and sensitivity for detecting CD44 in human samples, making it an essential reagent for flow cytometry experiments and other immunological assays.CD44 is known for its roles in cell-cell interactions, lymphocyte activation, and tumor metastasis, making it a key target in various research fields, including cancer biology, stem cell research, and inflammation studies.
The P2A1 antibody specifically recognizes CD44, allowing for precise identification and quantification of CD44-expressing cells in complex biological samples.With its validated performance in flow cytometry and compatibility with various experimental protocols, the Human CD44 Monoclonal Antibody PerCP-Cyanine5.5 Conjugated (P2A1) facilitates in-depth investigations into the functions and significance of CD44 in diverse physiological and pathological processes. Researchers can rely on this antibody to accurately interrogate CD44 expression patterns and dynamics, shedding light on its implications in health and disease.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P16070
Gene ID:
960
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from a low or mid level of intensity to high expression levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.