PE/Cyanine5 Anti-Human CD44 Antibody [Hermes-1] (AGEL2104)

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SKU:
AGEL2104
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine5 Anti-Human CD44 Antibody [Hermes-1]

The Human CD44 Monoclonal Antibody - PE/Cyanine5 Conjugated (J110) is designed for research applications involving CD44, a cell surface glycoprotein involved in cell adhesion and migration. This antibody, conjugated with PE and Cyanine5, offers dual-color detection capabilities, enhancing the efficiency of flow cytometry and other fluorescence-based assays.CD44, known for its versatility in mediating cell-cell and cell-matrix interactions, plays a crucial role in various physiological and pathological processes, such as inflammation, tumor metastasis, and stem cell homing.

The specificity and high binding affinity of the J110 antibody make it a valuable tool for studying CD44 expression and function in different cell types and tissues.With its ability to detect and quantify CD44 expression levels, this antibody is a valuable asset in research areas such as cancer biology, immunology, and regenerative medicine. By providing insights into the role of CD44 in disease progression and tissue regeneration, this antibody aids in advancing our understanding of cellular mechanisms and potential therapeutic targets.

Product Title:PE/Cyanine5 Anti-Human CD44 Antibody [Hermes-1]
SKU:AGEL2104
Size:20 Tests, 100 Tests, 200 Tests
Clone No:Hermes-1
Synonyms:LHR;PGP-I;CDw44;Epican;HUTCH-I;
Host Species:Rat
Reactivity:Human
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine5 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P16070
Gene ID:960
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from a low or mid level of intensity to high expression levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

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