The Human CD40 Monoclonal Antibody (PE Conjugated) G28-5 (AGEL2095) offered by AssayGenie is a specialized tool for immunology research, particularly focusing on CD40, a cell surface receptor essential for immune responses. This monoclonal antibody, conjugated with phycoerythrin (PE), is specifically designed for detecting and analyzing CD40 protein in human samples.CD40 is a crucial protein involved in immune system function, serving as a key mediator in immune cell communication and activation. By targeting CD40 with this monoclonal antibody, researchers can gain valuable insights into the role of CD40 in various cellular processes, including immune signaling and regulation.
This antibody is validated for use in flow cytometry applications, allowing for precise and reliable detection of CD40 in different cell types.The CD40 Monoclonal Antibody (PE Conjugated) G28-5 (AGEL2095) is an invaluable tool for studying immune responses, inflammation, and potential therapeutic targets in diseases such as cancer, autoimmune disorders, and inflammatory conditions. By enabling the visualization and characterization of CD40 protein expression, this antibody contributes to advancing our understanding of immune function and disease mechanisms.
Product Title:
PE Anti-Human CD40 Antibody [G28.5]
SKU:
AGEL2095
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
G28.5
Synonyms:
Bp50;CDw40;CD40L receptor;TNFRSF5;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
PE Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
PE
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P25942
Gene ID:
958
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand).