Biotin Anti-Human CD4 Antibody [RPA-T4] (AGEL0398)

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SKU:
AGEL0398
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
RPA-T4
Conjugation:
Biotin
Applications:
FC
Frequently bought together:

Description

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Biotin Anti-Human CD4 Antibody [RPA-T4]

The Human CD4 Monoclonal Antibody Biotin-Conjugated (RPA-T4) is a specialized antibody designed for research applications involving the CD4 cell surface molecule. CD4 is a crucial marker for T helper cells, playing a fundamental role in immune response regulation and coordination. This biotin-conjugated monoclonal antibody, clone RPA-T4, offers high specificity and sensitivity when detecting CD4 in human samples, making it an invaluable tool for immunology studies.With its ability to bind specifically to CD4, this monoclonal antibody opens up a wide range of investigative possibilities in the fields of immunology, infectious diseases, and autoimmune disorders.

By enabling precise detection and analysis of CD4-positive cells in various experimental settings, researchers can gain deeper insights into immune system function, T cell differentiation, and disease pathogenesis.The biotin conjugation of this monoclonal antibody provides added versatility, allowing for easy detection through techniques such as immunohistochemistry, flow cytometry, and immunoprecipitation. This flexibility makes the Human CD4 Monoclonal Antibody Biotin-Conjugated (RPA-T4) a valuable resource for studies seeking to understand the intricate mechanisms of immune response regulation and T cell-mediated immunity.

Product Title:Biotin Anti-Human CD4 Antibody [RPA-T4]
SKU:AGEL0398
Size:25µg, 100µg
Clone No:RPA-T4
Synonyms:T-cell surface glycoprotein CD4;CD4;T-cell surface antigen T4/Leu-3;CD4;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Biotin Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Biotin
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P01730
Gene ID:920
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD4, also known as T4/Leu-3, is a 55 kD single-chain type I transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed on most thymocytes, helper T cells, type II NKT cells, and monocytes/macrophages. CD4 is part of the TCR/CD3 complex, binds to β2 domain from the MHC class II molecule, and participates in TCR signal transduction. CD4 is the receptor of IL-16 and is a coreceptor for the human immunodeficiency virus (HIV) and human herpes virus 7 (HHV-7).

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