GenieFluor 647 Anti-Human CD35 Antibody [E11] (AGEL1016)

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SKU:
AGEL1016
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
Frequently bought together:

Description

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GenieFluor 647 Anti-Human CD35 Antibody [E11]

The Human CD35 Monoclonal Antibody (AF647 Conjugated) is a cutting-edge tool for research in the field of immunology and cell biology. This antibody, designated as E11-AGEL1016, is specifically designed to target CD35, a cell surface protein known for its role in immune regulation and complement system activation.Derived from a monoclonal antibody source, this antibody is conjugated with AF647, a fluorescent dye that allows for easy detection and visualization in a variety of experimental settings. Its high specificity for human CD35 makes it a reliable reagent for studying the functions and expression patterns of this important protein in diverse cell types and tissues.Researchers interested in understanding the intricate mechanisms of immune response modulation, complement activation, and inflammatory processes will find this CD35 antibody indispensable for their studies.

With its proven efficacy in applications such as flow cytometry, immunofluorescence, and immunohistochemistry, this antibody provides valuable insights into the intricate workings of the immune system and its implications in various health conditions.By delving into the intricate details of CD35 biology using this advanced antibody, scientists can unravel new avenues for therapeutic interventions in diseases involving aberrant immune responses, autoimmune disorders, and dysregulated inflammation. Illuminate your research with the Human CD35 Monoclonal Antibody (AF647 Conjugated) and pave the way for groundbreaking discoveries in immunology and beyond.

Product Title:GenieFluor 647 Anti-Human CD35 Antibody [E11]
SKU:AGEL1016
Size:20 Tests, 100 Tests, 200 Tests
Clone No:E11
Synonyms:Complement receptor type 1;CR1;C3b/C4b receptor;CD35;CR1;C3BR;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 647 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P17927
Gene ID:1378
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD35 is a type I single chain of glycoprotein, also known as C3b/C4b receptor, Complement Receptor type 1 or CR1. Four molecular weight allotypes (160kD, 190kD, 220kD, and 250kD) have been described. CD35 is expressed on granulocytes, monocytes, B cells, erythrocytes, and follicular dendritic cells, as well as subsets of NK and T cells. CD35 binds complement C3b, C4b, or iC3, and iC4, and plays important roles in both innate and adoptive immune response via mediating phagocytosis by granulocytes and monocytes. CD35 has also been reported to inhibit T-cell proliferation.

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