Human CD300E Recombinant Protein (RPPB3116)

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SKU:
RPPB3116
Product type:
Recombinant Protein
Size:
20ug
Species:
Human
Target:
CD300E
Synonyms:
CD300e Molecule
Synonyms:
CD300e Antigen
Synonyms:
CD300LE
Synonyms:
IREM2
Source:
Escherichia Coli
Uniprot:
Q496F6
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Description

Product Name:Human CD300E Recombinant Protein
Product Code:RPPB3116
Size:20µg
Species:Human
Target:CD300E
Synonyms:CD300e Molecule, CD300e Antigen, CD300LE, IREM2, CLM2, Immune Receptor Expressed On Myeloid Cells 2, Polymeric Immunoglobulin Receptor 2,CD300 Antigen Like Family Member E, CD300 Antigen-Like Family Member E,Poly-Ig Receptor 2, CMRF35-A5, PIgR2, CMRF35-Like Molecule 2, CMRF35A5, CD300E.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:CD300E protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0).
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSLKGPGSV TGTAGDSLTV WCQYESMYKG YNKYWCRGQY DTSCESIVET KGEEKVERNG RVSIRDHPEA LAFTVTMQNL NEDDAGSYWC KIQTVWVLDS WSRDPSDLVR VYVSPAITTP RRTTHPATPP IFLVVNPGRN LSTGEVLTQN SGFRLSSPH

CMRF35-like molecule 2 precursor (CD300E) is a member of the CD300 family. CD300E is a 205 amino acid single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. While interacting with DAP12, CD300E probably performs as an activating receptor. CD300E is present on the surface of mature hematopoietic cells of the monocyte & myeloid lineages.

CD300E Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids (18-173 a.a) and having a molecular mass of 19.9kDa.CD300E is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:CD300E: Probably acts as an activating receptor. Belongs to the CD300 family.
UniProt Protein Details:

Protein type:Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: 17q25.1

Cellular Component: plasma membrane

Biological Process: innate immune response; regulation of immune response

NCBI Summary:This gene encodes a member of the CD300 glycoprotein family of cell surface proteins expressed on myeloid cells. The protein interacts with the TYRO protein tyrosine kinase-binding protein and is thought to act as an activating receptor. [provided by RefSeq, Nov 2012]
UniProt Code:Q496F6
NCBI GenInfo Identifier:296434454
NCBI Gene ID:342510
NCBI Accession:Q496F6.2
UniProt Secondary Accession:Q496F6,Q7Z7I3, B4DNS1,
UniProt Related Accession:Q496F6
Molecular Weight:22,918 Da
NCBI Full Name:CMRF35-like molecule 2
NCBI Synonym Full Names:CD300e molecule
NCBI Official Symbol:CD300E  
NCBI Official Synonym Symbols:CLM2; CLM-2; IREM2; PIgR2; IREM-2; PIgR-2; CD300LE; CMRF35-A5  
NCBI Protein Information:CMRF35-like molecule 2
UniProt Protein Name:CMRF35-like molecule 2
UniProt Synonym Protein Names:CD300 antigen-like family member E; CMRF35-A5; Immune receptor expressed on myeloid cells 2; IREM-2; Polymeric immunoglobulin receptor 2; PIgR-2; PIgR2; Poly-Ig receptor 2; CD_antigen: CD300e
Protein Family:CMRF35-like molecule
UniProt Gene Name:CD300E  
UniProt Entry Name:CLM2_HUMAN
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