Purified Anti-Human CD29 Antibody [TS2/16.2.1] (AGEL0212)

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SKU:
AGEL0212
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
TS2/16.2.1
Conjugation:
Unconjugated
Applications:
FC
IHC
IF
IP
Frequently bought together:

Description

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Purified Anti-Human CD29 Antibody [TS2/16.2.1]

The Human CD29 Monoclonal Antibody (TS2-16-2-1) from Assay Genie (AGEL0212) is a cutting-edge tool designed for research in the field of cell biology and immunology. This monoclonal antibody is specifically developed to target the CD29 antigen, also known as integrin beta-1, a key cell surface protein involved in cell adhesion and signaling.The AGEL0212 antibody offers high specificity and sensitivity in detecting CD29 in human samples, making it a reliable choice for various experimental applications. Its versatility allows for use in techniques such as immunohistochemistry, flow cytometry, and immunofluorescence, providing researchers with multiple options for studying CD29 expression and function in different cell types and tissues.CD29 is a vital protein involved in cell-matrix interactions, cell migration, and signaling pathways essential for physiological processes like tissue development, immune response, and wound healing.

Dysregulation of CD29 expression or activity has been associated with various diseases, including cancer, inflammatory disorders, and cardiovascular conditions. By using the AGEL0212 antibody to investigate CD29, researchers can gain valuable insights into the role of this integrin in health and disease, potentially leading to the development of novel therapeutic strategies targeting CD29-mediated pathways.In summary, the Human CD29 Monoclonal Antibody (TS2-16-2-1) from Assay Genie (AGEL0212) is a powerful research tool that enables precise detection and analysis of CD29, facilitating in-depth exploration of its functions and mechanisms in both normal and pathological conditions. Its quality, reliability, and applicability make it an indispensable asset for scientists and investigators dedicated to advancing our understanding of cell biology and immunology.

Product Title:Purified Anti-Human CD29 Antibody [TS2/16.2.1]
SKU:AGEL0212
Size:25µg, 100µg
Clone No:TS2/16.2.1
Synonyms:Integrin beta-1;ITB1;Itgb1;Fibronectin receptor subunit beta;VLA-4 subunit beta;CD29;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Purified Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Unconjugated
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P05556
Gene ID:3688
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD29 is a 130 kD single chain type I glycoprotein also known as integrin β1, VLA-β chain, or gpIIa. It is broadly expressed on a majority of hematopoietic and non-hematopoietic cells, including leukocytes (although at low level on granulocytes), platelets, fibroblasts, endothelial cells, epithelial cells, and mast cells. CD29 is a member of the integrin family. It is non-covalently associated with integrin α1-α6 chains to form VLA-1 to VLA-6 molecules, respectively. Integrins, which include CD29, bind to several cell surface (e.g. VCAM-1, MadCAM-1) and extracellular matrix molecules. CD29 acts as a fibronectin receptor and is involved in a variety of cell-cell and cell-matrix interactions.

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