Human CD164 Recombinant Protein (RPPB3041)
- SKU:
- RPPB3041
- Product type:
- Recombinant Protein
- Size:
- 10ug
- Species:
- Human
- Target:
- CD164
- Synonyms:
- CD164 Molecule
- Multi-Glycosylated Core Protein 24
- CD164 Antigen
- Sialomucin
- Source:
- Sf9 Insect cells
- Uniprot:
- Q04900
Frequently bought together:
Description
| Product Name: | Human CD164 Recombinant Protein |
| Product Code: | RPPB3041 |
| Size: | 10µg |
| Species: | Human |
| Target: | CD164 |
| Synonyms: | CD164 Molecule, Multi-Glycosylated Core Protein 24, CD164 Antigen, Sialomucin, Endolyn MGC-24v, MGC-24, MUC-24, Deafness, Autosomal Dominant 66, Sialomucin Core Protein 24, DFNA66, CD164. |
| Source: | Sf9 Insect cells |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | CD164 protein solution (0.5mg/ml) contains 10% glycerol & Phosphate buffered saline (pH7.4). |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | ADPDKNTTQH PNVTTLAPIS NVTSAPVTSL PLVTTPAPET CEGRNSCVSC FNVSVVNTTC FWIECKDESY CSHNSTVSDC QVGNTTDFCS VSTATPVPTA NSTAKPTVQP SPSTTSKTVT TSGTTNNTVT PTSQPVRKST FDHHHHHH |
CD164, also known as Multi-Glycosylated Core Protein 24 is amember of the CD164 family.
CD164 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain (24-162 a.a.) and fused to a 6 aa His Tag at C-terminus containing a total of 148 amino acids and having a molecular mass of 15.6kDa.CD164 shows multiple bands between 28-57kDa on SDS-PAGE, reducing conditions and purified by proprietary chromatographic techniques.
| UniProt Protein Function: | Sialomucin that may play a key role in hematopoiesis by facilitating the adhesion of CD34+ cells to the stroma and by negatively regulating CD34+CD38(lo/-) cell proliferation. Modulates the migration of umbilical cord blood CD133+ cells and this is mediated through the CXCL12/CXCR4 axis. May play an important role in prostate cancer metastasis and the infiltration of bone marrow by cancer cells. Promotes myogenesis by enhancing CXCR4-dependent cell motility. Positively regulates myoblast migration and promotes myoblast fusion into myotubes. |
| NCBI Summary: | This gene encodes a transmembrane sialomucin and cell adhesion molecule that regulates the proliferation, adhesion and migration of hematopoietic progenitor cells. The encoded protein also interacts with the C-X-C chemokine receptor type 4 and may regulate muscle development. Elevated expression of this gene has been observed in human patients with Sezary syndrome, a type of blood cancer, and a mutation in this gene may be associated with impaired hearing. [provided by RefSeq, Oct 2016] |
| UniProt Code: | Q04900 |
| NCBI GenInfo Identifier: | 257051036 |
| NCBI Gene ID: | 8763 |
| NCBI Accession: | Q04900.2 |
| UniProt Related Accession: | Q04900 |
| Molecular Weight: | 16kDa; 19kDa; 20kDa |
| NCBI Full Name: | Sialomucin core protein 24 |
| NCBI Synonym Full Names: | CD164 molecule |
| NCBI Official Symbol: | CD164 |
| NCBI Official Synonym Symbols: | DFNA66; MGC-24; MUC-24; MGC-24v; endolyn |
| NCBI Protein Information: | sialomucin core protein 24 |
| UniProt Protein Name: | Sialomucin core protein 24 |
| UniProt Synonym Protein Names: | Endolyn; Multi-glycosylated core protein 24; MGC-24; MGC-24v; CD_antigen: CD164 |
| Protein Family: | CD164 sialomucin-like 2 protein |
| UniProt Gene Name: | CD164 |
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