Human CD164 Recombinant Protein (RPPB3041)

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SKU:
RPPB3041
Product type:
Recombinant Protein
Size:
10ug
Species:
Human
Target:
CD164
Synonyms:
CD164 Molecule
Synonyms:
Multi-Glycosylated Core Protein 24
Synonyms:
CD164 Antigen
Synonyms:
Sialomucin
Source:
Sf9 Insect cells
Uniprot:
Q04900
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Description

Product Name:Human CD164 Recombinant Protein
Product Code:RPPB3041
Size:10µg
Species:Human
Target:CD164
Synonyms:CD164 Molecule, Multi-Glycosylated Core Protein 24, CD164 Antigen, Sialomucin, Endolyn MGC-24v, MGC-24, MUC-24, Deafness, Autosomal Dominant 66, Sialomucin Core Protein 24, DFNA66, CD164.
Source:Sf9 Insect cells
Physical Appearance:Sterile filtered colorless solution.
Formulation:CD164 protein solution (0.5mg/ml) contains 10% glycerol & Phosphate buffered saline (pH7.4).
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 85.0% as determined by SDS-PAGE.
Amino Acid Sequence:ADPDKNTTQH PNVTTLAPIS NVTSAPVTSL PLVTTPAPET CEGRNSCVSC FNVSVVNTTC FWIECKDESY CSHNSTVSDC QVGNTTDFCS VSTATPVPTA NSTAKPTVQP SPSTTSKTVT TSGTTNNTVT PTSQPVRKST FDHHHHHH

CD164, also known as Multi-Glycosylated Core Protein 24 is amember of the CD164 family.

CD164 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain (24-162 a.a.) and fused to a 6 aa His Tag at C-terminus containing a total of 148 amino acids and having a molecular mass of 15.6kDa.CD164 shows multiple bands between 28-57kDa on SDS-PAGE, reducing conditions and purified by proprietary chromatographic techniques.

UniProt Protein Function:Sialomucin that may play a key role in hematopoiesis by facilitating the adhesion of CD34+ cells to the stroma and by negatively regulating CD34+CD38(lo/-) cell proliferation. Modulates the migration of umbilical cord blood CD133+ cells and this is mediated through the CXCL12/CXCR4 axis. May play an important role in prostate cancer metastasis and the infiltration of bone marrow by cancer cells. Promotes myogenesis by enhancing CXCR4-dependent cell motility. Positively regulates myoblast migration and promotes myoblast fusion into myotubes.
NCBI Summary:This gene encodes a transmembrane sialomucin and cell adhesion molecule that regulates the proliferation, adhesion and migration of hematopoietic progenitor cells. The encoded protein also interacts with the C-X-C chemokine receptor type 4 and may regulate muscle development. Elevated expression of this gene has been observed in human patients with Sezary syndrome, a type of blood cancer, and a mutation in this gene may be associated with impaired hearing. [provided by RefSeq, Oct 2016]
UniProt Code:Q04900
NCBI GenInfo Identifier:257051036
NCBI Gene ID:8763
NCBI Accession:Q04900.2
UniProt Related Accession:Q04900
Molecular Weight:16kDa; 19kDa; 20kDa
NCBI Full Name:Sialomucin core protein 24
NCBI Synonym Full Names:CD164 molecule
NCBI Official Symbol:CD164  
NCBI Official Synonym Symbols:DFNA66; MGC-24; MUC-24; MGC-24v; endolyn  
NCBI Protein Information:sialomucin core protein 24
UniProt Protein Name:Sialomucin core protein 24
UniProt Synonym Protein Names:Endolyn; Multi-glycosylated core protein 24; MGC-24; MGC-24v; CD_antigen: CD164
Protein Family:CD164 sialomucin-like 2 protein
UniProt Gene Name:CD164  
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