PE/Cyanine5.5 Anti-Human CD11c Antibody [BU15] (AGEL1462)

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SKU:
AGEL1462
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine5.5 Anti-Human CD11c Antibody [BU15]

The Human CD11c Monoclonal Antibody (PE/Cyanine5.5 Conjugated) (BU15, AGEL1462) is a vital tool for researchers studying the CD11c cell surface molecule, a marker of dendritic cells and monocytes involved in immune responses. This antibody, produced using hybridoma technology, is highly specific for human samples and is validated for use in flow cytometry applications. It allows for the precise detection and analysis of CD11c expression in various cell populations, making it ideal for studies in immunology, inflammation, and infectious diseases.

CD11c is a key player in immune surveillance, antigen presentation, and inflammation, making it a valuable target for research into diseases such as cancer, autoimmune disorders, and infectious diseases. Understanding the role of CD11c in immune regulation and disease pathology is essential for developing effective therapies that target or modulate immune responses in these conditions. Researchers can rely on the accuracy and reliability of this antibody to advance their studies and contribute to the field of immunology.

Product Title:PE/Cyanine5.5 Anti-Human CD11c Antibody [BU15]
SKU:AGEL1462
Size:20 Tests, 100 Tests, 200 Tests
Clone No:BU15
Synonyms:Integrin alpha-X;Itgax;CD11 antigen-like family member C;Leukocyte adhesion receptor p150+95;CD11c;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE/Cyanine5.5 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P20702
Gene ID:3687
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11c is a 145-150 kD type I transmembrane glycoprotein also known as integrin αX and CR4. CD11c non-covalently associates with integrin β2 (CD18) and is expressed on monocytes/macrophages, dendritic cells, granulocytes, NK cells, and subsets of T and B cells. CD11c has been reported to play a role in adhesion and CTL killing through its interactions with fibrinogen, CD54, and iC3b.

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