The Human CD11a Monoclonal Antibody PE-Conjugated (R7-1) is a cutting-edge tool for researchers delving into the intricate world of immune system interactions. CD11a, a vital cell surface protein involved in immune responses, is the focus of this powerful antibody. The Monoclonal Antibody, developed with precision and expertise, offers high reactivity and specificity for human samples, ensuring reliable and accurate results in various experimental settings.This innovative antibody, conjugated with Phycoerythrin (PE) for enhanced detection capabilities, is meticulously validated for its effectiveness in flow cytometry applications. By specifically binding to CD11a, this antibody enables precise detection and analysis of this critical immune molecule in a wide range of cell types.
Its versatility and reliability make it an indispensable asset for studies in immunology, inflammation, and cancer research.CD11a, a key component of the immune system, plays a pivotal role in cell adhesion and signaling processes essential for immune cell function. By targeting CD11a with this advanced monoclonal antibody, researchers can gain valuable insights into immune responses, inflammatory pathways, and potential therapeutic interventions for various diseases. Harnessing the power of this antibody opens up new possibilities for unraveling the complexities of immune regulation and developing targeted strategies for treating immune-related conditions.
Product Title:
PE Anti-Human CD11a Antibody [R7-1]
SKU:
AGEL2086
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
R7-1
Synonyms:
Integrin alpha-L;LFA-1A;CD11A;ITGAL;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
PE Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
PE
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P20701
Gene ID:
3683
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).