Human CAPSL Recombinant Protein (RPPB2981)

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SKU:
RPPB2981
Product type:
Recombinant Protein
Size:
20ug
Species:
Human
Target:
CAPSL
Synonyms:
Calcyphosine-like protein
Synonyms:
CAPSL
Synonyms:
MGC26610
Source:
Escherichia Coli
Uniprot:
Q8WWF8
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Description

Product Name:Human CAPSL Recombinant Protein
Product Code:RPPB2981
Size:20µg
Species:Human
Target:CAPSL
Synonyms:Calcyphosine-like protein, CAPSL, MGC26610.
Source:Escherichia Coli
Physical Appearance:CAPSL is supplied as a sterile filtered clear solution.
Formulation:CAPSL protein at 1mg/ml in 20mM Tris-HCL, pH-8, 0.2M NaCl, 5mM DTT and 20% Glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MAGTARHDRE MAIQAKKKLT TATDPIERLR LQCLARGSAG IKGLGRVFRI MDDDNNRTLD FKEFMKGLND YAVVMEKEEV EELFQRFDKD GNGTIDFNEF LLTLRPPMSR ARKEVIMQAF RKLDKTGDGV ITIEDLREVY NAKHHPKYQN GEWSEEQVFR KFLDNFDSPY DKDGLVTPEE FMNYYAGVSA SIDTDVYFII MMRTAWKL

CAPSL is a calcium-binding protein holding two conserved calcium-binding motifs (EF-hands) which are found in a superfamily of calcium sensors and calcium signal modulators. In addition, the CAPSL gene is in the same linkage disequilibrium (LD) block as the IL7R gene and there is well known association between the CAPSL-IL7R locus and type 1 diabetes.

CAPSL Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 228 amino acids (1-208) and having a molecular mass of 26.3 kDa.The CAPSL is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.

UniProt Protein Function:CAPSL: Chromosomal Location of Human Ortholog: 5p13.2Cellular Component: cytoplasmMolecular Function: calcium ion binding
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q8WWF8
NCBI GenInfo Identifier:110835717
NCBI Gene ID:133690
NCBI Accession:NP_653248.3
UniProt Secondary Accession:Q8WWF8
UniProt Related Accession:Q8WWF8
Molecular Weight:
NCBI Full Name:calcyphosin-like protein
NCBI Synonym Full Names:calcyphosine-like
NCBI Official Symbol:CAPSL  
NCBI Official Synonym Symbols:
NCBI Protein Information:calcyphosin-like protein
UniProt Protein Name:Calcyphosin-like protein
UniProt Synonym Protein Names:
Protein Family:Calcyphosin-like protein
UniProt Gene Name:CAPSL  
UniProt Entry Name:CAPSL_HUMAN
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