Human ASS1 Recombinant Protein (RPES3002)
- SKU:
- RPES3002
- Product type:
- Recombinant Protein
- Host species:
- E.coli
- Reactivity:
- Human
Frequently bought together:
Description
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Human ASS1 Recombinant Protein
Argininosuccinate Synthase (ASS1) is an urea cycle enzyme with a tetrameric structure composed of identical subunits. ASS1 is involved in the synthesis of arginine and catalyzes that condensation of citrulline and aspartate to argininosuccinate using ATP. ASS1 is important to the urea cycle as it catalyzes the important second last step in the arginine biosynthetic pathway. ASS1 mainly expressed in periportal hepatocytes, but also in most other body tissues. A deficiency of ASS1 causes citrullinemia (CTLN1), an autosomal recessive disease which is characterized by severe vomiting spells and mental retardation.
Product Name: | Human ASS1 Recombinant Protein (RPES3002) |
Product Code: | RPES3002 |
Size: | 10µg |
Species: | Human |
Expressed Host: | E.coli |
Synonyms: | Argininosuccinate Synthase, Citrulline--Aspartate Ligase, ASS1, ASS |
Accession: | P00966 |
Sequence: | Met 1-Lys412 |
Fusion tag: | N-6His |
Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
Protein Construction: | Recombinant Human Argininosuccinate Synthase is produced by our E.coli expression system and the target gene encoding Met1-Lys412 is expressed with a 6His tag at the N-terminus. |
Purity: | > 95 % as determined by reducing SDS-PAGE. |
Mol Mass: | 42.8 kDa |
AP Mol Mass: | 50 kDa |
Formulation: | Supplied as a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, 50mM Imidazole, 1mM DTT, 40% Glycerol, pH 7.5. |
Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |