Human ARL5B Recombinant Protein (RPPB2793)

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SKU:
RPPB2793
Product type:
Recombinant Protein
Size:
20ug
Species:
Human
Target:
ARL5B
Synonyms:
ADP-ribosylation factor-like protein 5B
Synonyms:
ADP-ribosylation factor-like protein 8
Synonyms:
ARL5B
Synonyms:
ARL8
Source:
Escherichia Coli
Uniprot:
Q96KC2
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Description

Product Name:Human ARL5B Recombinant Protein
Product Code:RPPB2793
Size:20µg
Species:Human
Target:ARL5B
Synonyms:ADP-ribosylation factor-like protein 5B, ADP-ribosylation factor-like protein 8, ARL5B, ARL8.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:ARL5B protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 2mM DTT, 30% glycerol, 0.1M NaCl and 1mM EDTA.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGLIFAKLWS LFCNQEHKVI IVGLDNAGKT TILYQFLMNE VVHTSPTIGS NVEEIVVKNT HFLMWDIGGQ ESLRSSWNTY YSNTEFIILV VDSIDRERLA ITKEELYRML AHEDLRKAAV LIFANKQDMK GCMTAAEISK YLTLSSIKDH PWHIQSCCAL TGEGLCQGLE WMTSRIGVR

ADP-ribosylation factor-like protein 5B (ARL5B) is a member of a family of proteins which are structurally similar to ADP-ribosylation factors. ARLs and ARFs belong to the RAS superfamily of regulatory GTPases. ARL5B is most closely related to ARL5, with which it shares 80% sequence identity. Furthermore, Human ARL5B shares 100% identity with mouse ARL8 and 71% identity with the Drosophila homolog.

ARL5B Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 199 amino acids (1-179 a.a.) and having a molecular mass of 22.5kDa.ARL5B is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:ARL5B: Binds and exchanges GTP and GDP. Belongs to the small GTPase superfamily. Arf family.Protein type: G protein, monomeric; G protein, monomeric, ARFChromosomal Location of Human Ortholog: 10p12.31
UniProt Protein Details:
NCBI Summary:ARL5B (ARL8) belongs to a family of proteins that are structurally similar to ADP-ribosylation factors (ARFs; see MIM 103180). ARLs and ARFs are part of the RAS superfamily of regulatory GTPases.[supplied by OMIM, Nov 2010]
UniProt Code:Q96KC2
NCBI GenInfo Identifier:34922029
NCBI Gene ID:221079
NCBI Accession:Q96KC2.1
UniProt Secondary Accession:Q96KC2
UniProt Related Accession:Q96KC2
Molecular Weight:20,375 Da
NCBI Full Name:ADP-ribosylation factor-like protein 5B
NCBI Synonym Full Names:ADP ribosylation factor like GTPase 5B
NCBI Official Symbol:ARL5B  
NCBI Official Synonym Symbols:ARL8  
NCBI Protein Information:ADP-ribosylation factor-like protein 5B
UniProt Protein Name:ADP-ribosylation factor-like protein 5B
UniProt Synonym Protein Names:ADP-ribosylation factor-like protein 8
Protein Family:ADP-ribosylation factor-like protein
UniProt Gene Name:ARL5B  
UniProt Entry Name:ARL5B_HUMAN
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