Human ARL14 Recombinant Protein (RPPB2785)

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SKU:
RPPB2785
Product type:
Recombinant Protein
Size:
20ug
Species:
Human
Target:
ARL14
Synonyms:
ADP-ribosylation factor-like protein 14
Synonyms:
ADP-ribosylation factor 7
Synonyms:
ARL14
Synonyms:
ARF7
Source:
Escherichia Coli
Uniprot:
Q8N4G2
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Description

Product Name:Human ARL14 Recombinant Protein
Product Code:RPPB2785
Size:20µg
Species:Human
Target:ARL14
Synonyms:ADP-ribosylation factor-like protein 14, ADP-ribosylation factor 7, ARL14, ARF7, FLJ22595.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:ARL14 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 2mM DTT, 40% glycerol, 200mM NaCl and 1mM EDTA.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSLGSKNPQ TKQAQVLLLG LDSAGKSTLL YKLKLAKDIT TIPTIGFNVE MIELERNLSL TVWDVGGQEK MRTVWGCYCE NTDGLVYVVD STDKQRLEES QRQFEHILKN EHIKNVPVVL LANKQDMPGA LTAEDITRMF KVKKLCSDRN WYVQPCCALT GEGLAQGFRK LTGFVKSHMK SRGDTLAFFK QN

ADP-ribosylation factor-like 14 (ARL14) is a developmentally regulated member of the ADP-ribosylation factor/ARF-like protein (ARF/ARL) family of Ras-related GTPases. ARL14 is GTPase which recruits MYO1E to MHC class II-containing vesicles via the effector protein C11orf46/ARF7EP and thus controls the movement of these vesicles along the actin cytoskeleton in dendritic cells. MHC-II transport was controlled by the GTPase ARL14/ARF7, which recruits the motor myosin 1E via an effector protein ARF7EP.

ARL14 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 212 amino acids (1-192 a.a.) and having a molecular mass of 23.8kDa (Molecular weight on SDS-PAGE will appear higher).ARL14 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q8N4G2
NCBI GenInfo Identifier:21707815
NCBI Gene ID:80117
NCBI Accession:BC034354
UniProt Secondary Accession:Q8N4G2,Q9H655
UniProt Related Accession:Q8N4G2
Molecular Weight:21,588 Da
NCBI Full Name:Homo sapiens ADP-ribosylation factor-like 14, mRNA
NCBI Synonym Full Names:ADP-ribosylation factor-like 14
NCBI Official Symbol:ARL14  
NCBI Official Synonym Symbols:ARF7  
NCBI Protein Information:ADP-ribosylation factor-like protein 14; ADP-ribosylation factor 7
UniProt Protein Name:
UniProt Synonym Protein Names:
Protein Family:Auxin response factor
UniProt Gene Name:
UniProt Entry Name:
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