Human ANGPTL6 Recombinant Protein (RPPB0042)

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SKU:
RPPB0042
Product type:
Recombinant Protein
Size:
10ug
Species:
Human
Target:
ANGPTL6
Synonyms:
Angiopoietin-Like Protein 6
Synonyms:
Angiopoietin-Related Protein 5
Synonyms:
Angiopoietin-Related Growth Factor
Synonyms:
Angiopoietin-Related Protein 6
Source:
Escherichia Coli
Uniprot:
Q8NI99
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Description

Product Name:Human ANGPTL6 Recombinant Protein
Product Code:RPPB0042
Size:10µg
Species:Human
Target:ANGPTL6
Synonyms:Angiopoietin-Like Protein 6, Angiopoietin-Related Protein 5, Angiopoietin-Related Growth Factor, Angiopoietin-Related Protein 6, AGF, ARP5.
Source:Escherichia Coli
Physical Appearance:White lyophilized (freeze-dried) powder.
Formulation:Filtered (0.4 µm) and lyophilized from a 0.5mg/ml solution containing 0.05M Acetate buffer pH 4.0.
Solubility:Add 0.1M acetate buffer pH 4.0 to prepare a working stock solution of 0.5 mg/ml and let the lyophilized pellet dissolve completely. For conversion into higher pH value, we recommend intensive dilution by relevant buffer to a concentration of 10?g/ml. In higher concentrations the solubility of this antigen is limited. Product is not sterile! Please filter the product by appropriate sterile filter before using it in the cell culture.
Stability:Lyophilized ANGPTL6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ANGPTL6 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MKHHHHHHAS RAGAPRCTYT FVLPPQKFTG AVCWSGPAST RATPEAANAS ELAALRMRVG RHEELLRELQ RLAAADGAVA GEVRALRKES RGLSARLGQL RAQLQHEAGP GAGPGADLGA EPAAALALLG ERVLNASAEA QRAAARFHQL DVKFRELAQL VTQQSSLIAR LERLCPGGAG GQQQVLPPPP LVPVVPVRLV GSTSDTSRML DPAPEPQRDQ TQRQQEPMAS PMPAGHPAVP TKPVGPWQDC AEARQAGHEQ SGVYELRVGR HVVSVWCEQQ LEGGGWTVIQ RRQDGSVNFF TTWQHYKAGF GRPDGEYWLG LEPVYQLTSR GDHELLVLLE DWGGRGARAH YDGFSLEPES DHYRLRLGQY HGDAGDSLSW HNDKPFSTVD RDRDSYSGNC ALYQRGGWWY HACAHSNLNG VWHHGGHYRS RYQDGVYWAE FRGGAYSLRK AAMLIRPLKL 

ANGPTL6 is a protein-coding gene which takes part is several processes. ANGPTL6 is involved in the wound healing process, promotes the chemotactic activity of endothelial cells and induce neovascularization. ANGPTL6 also counteracts high-fat diet-induced obesity and related insulin resistance through increased energy expenditure. Additionally ANGPTL6 promotes epidermal proliferation, remodeling and regeneration. Diseases linked with ANGPTL6 include enterobiasis, and gnathomiasis.

ANGPTL6 Human Recombinant produced in E.coli is a polypeptide chain containing 460 amino acids and having a total molecular mass of 50.7 kDa. ANGPTL6 contains a N-Terminal 10 aa His-Tag.

UniProt Protein Function:ANGPTL6: May play a role in the wound healing process. May promote epidermal proliferation, remodeling and regeneration. May promote the chemotactic activity of endothelial cells and induce neovascularization. May counteract high-fat diet-induced obesity and related insulin resistance through increased energy expenditure.
UniProt Protein Details:

Protein type:Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: secretory granule

Biological Process: angiogenesis; cell differentiation

UniProt Code:Q8NI99
NCBI GenInfo Identifier:29893555
NCBI Gene ID:83854
NCBI Accession:NP_114123.2
UniProt Secondary Accession:Q8NI99,Q9BZZ0, A5PKV7,
UniProt Related Accession:Q8NI99
Molecular Weight:51,694 Da
NCBI Full Name:angiopoietin-related protein 6
NCBI Synonym Full Names:angiopoietin-like 6
NCBI Official Symbol:ANGPTL6  
NCBI Official Synonym Symbols:AGF; ARP5  
NCBI Protein Information:angiopoietin-related protein 6
UniProt Protein Name:Angiopoietin-related protein 6
UniProt Synonym Protein Names:Angiopoietin-like protein 6; Angiopoietin-related growth factor; Angiopoietin-related protein 5
Protein Family:Angiopoietin-related protein
UniProt Gene Name:ANGPTL6  
UniProt Entry Name:ANGL6_HUMAN
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