Human AKR1C4 Recombinant Protein (RPES2308)

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SKU:
RPES2308
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
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Description

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Human AKR1C4 Recombinant Protein

Aldo-Keto Reductase 1C4/AKR1C4 is a member of the aldo/keto reductase family that consists of more than 40 known enzymes and proteins. AKR1C4 has highly expressed in Liver. It can catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. AKR1C4 catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-?-Androstan-3-?,17-β-diol (3-?-diol). In addition, AKR1C4 also has some 20-?-Hydroxysteroid Dehydrogenase activity.

Product Name:Human AKR1C4 Recombinant Protein (RPES2308)
Product Code:RPES2308
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Aldo-Keto Reductase Family 1 Member C4, 3-Alpha-HSD1, 3-Alpha-Hydroxysteroid Dehydrogenase Type I, Chlordecone Reductase, CDR, Dihydrodiol Dehydrogenase 4, DD-4, DD4, HAKRA, AKR1C4, CHDR
Accession:P17516
Sequence:Met 1-Tyr323
Fusion tag:N-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Aldo-Keto Reductase Family 1 Member C4 is produced by our E.coli expression system and the target gene encoding Met1-Tyr323 is expressed with a 6His tag at the N-terminus.
Purity:> 90 % as determined by reducing SDS-PAGE.
Mol Mass:39.3 kDa
AP Mol Mass:26&38 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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