Human AGR3 Recombinant Protein (RPPB2716)

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SKU:
RPPB2716
Product type:
Recombinant Protein
Size:
20ug
Species:
Human
Target:
AGR3
Synonyms:
Anterior gradient protein 3 homolog
Synonyms:
AG-3
Synonyms:
AG3
Synonyms:
hAG-3
Source:
Escherichia Coli
Uniprot:
Q8TD06
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Description

Product Name:Human AGR3 Recombinant Protein
Product Code:RPPB2716
Size:20µg
Species:Human
Target:AGR3
Synonyms:Anterior gradient protein 3 homolog, AG-3, AG3, hAG-3, Breast cancer membrane protein 11, AGR3, BCMP11, UNQ642/PRO1272, HAG3, PDIA18.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:AGR3 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMIAIKKE KRPPQTLSRG WGDDITWVQT YEEGLFYAQK SKKPLMVIHH LEDCQYSQAL KKVFAQNEEI QEMAQNKFIM LNLMHETTDK NLSPDGQYVP RIMFVDPSLT VRADIAGRYS NRLYTYEPRD LPLLIENMKK ALRLIQSEL

Anterior gradient protein 3 homolog precursor (AGR3) is a secreted cytoplasmic protein that is involved in metastasis induction and p53 tumor suppressor inhibition. AGR3 may function as molecular marker and potential therapeutic target for hormone-responsive breast tumors.

AGR3 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 169 amino acids (22-166 a.a) and having a molecular mass of 19.5kDa.AGR3 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:AGR3: Belongs to the AGR family.Protein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 7p21.1Cellular Component: extracellular regionMolecular Function: protein binding
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q8TD06
NCBI GenInfo Identifier:28827801
NCBI Gene ID:155465
NCBI Accession:NP_789783.1
UniProt Secondary Accession:Q8TD06,A4D120
UniProt Related Accession:Q8TD06
Molecular Weight:19,171 Da
NCBI Full Name:anterior gradient protein 3 homolog
NCBI Synonym Full Names:anterior gradient 3 homolog (Xenopus laevis)
NCBI Official Symbol:AGR3  
NCBI Official Synonym Symbols:AG3; HAG3; hAG-3; BCMP11; PDIA18  
NCBI Protein Information:anterior gradient protein 3 homolog; AG-3; anterior gradient homolog 3; breast cancer membrane protein 11; protein disulfide isomerase family A, member 18
UniProt Protein Name:Anterior gradient protein 3 homolog
UniProt Synonym Protein Names:Breast cancer membrane protein 11
Protein Family:Anterior gradient protein
UniProt Gene Name:AGR3  
UniProt Entry Name:AGR3_HUMAN
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