Human ADH1A Recombinant Protein (RPPB5790)
- SKU:
- RPPB5790
- Product type:
- Recombinant Protein
- Size:
- 20ug
- Species:
- Human
- Target:
- ADH1A
- Synonyms:
- Alcohol dehydrogenase 1A
- Alcohol dehydrogenase subunit alpha
- ADH1A
- ADH1
- Source:
- Escherichia Coli
- Uniprot:
- P07327
Description
| Product Name: | Human ADH1A Recombinant Protein |
| Product Code: | RPPB5790 |
| Size: | 20µg |
| Species: | Human |
| Target: | ADH1A |
| Synonyms: | Alcohol dehydrogenase 1A, Alcohol dehydrogenase subunit alpha, ADH1A, ADH1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The ADH1A solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 10% glycerol and 0.1M NaCl. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MSTAGKVIKC KAAVLWELKK PFSIEEVEVA PPKAHEVRIK MVAVGICGTD DHVVSGTMVT PLPVILGHEA AGIVESVGEG VTTVKPGDKV IPLAIPQCGK CRICKNPESN YCLKNDVSNP QGTLQDGTSR FTCRRKPIHH FLGISTFSQY TVVDENAVAK IDAASPLEKV CLIGCGFSTG YGSAVNVAKV TPGSTCAVFG LGGVGLSAIM GCKAAGAARI IAVDINKDKF AKAKELGATE CINPQDYKKP IQEVLKEMTD GGVDFSFEVI GRLDTMMASL LCCHEACGTS VIVGVPPDSQ NLSMNPMLLL TGRTWKGAIL GGFKSKECVP KLVADFMAKK FSLDALITHV LPFEKINEGF DLLHSGKSIR TILMF |
Alcohol dehydrogenase 1A (ADH1A) is a member of the alcohol dehydrogenase family. ADH1A has a key role in ethanol metabolism. ADH1A along with coenzyme NAD catalyzes the reversible conversion of organic alcohols to ketones or aldehydes. The physiologic function of ADH1A in the liver is the elimination of ethanol formed by microorganisms in the intestinal tract. ADH1A is monomorphic and predominant in fetal and infant livers, growing to be less active in gestation and only weakly active during adulthood.
ADH1A Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 395 amino acids (1-375) and having a molecular mass of 42kDa.ADH1A is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Code: | P07327 |
| NCBI GenInfo Identifier: | 4501929 |
| NCBI Gene ID: | 124 |
| NCBI Accession: | NP_000658.1 |
| UniProt Secondary Accession: | P07327,Q17R68, A8K3E3, |
| UniProt Related Accession: | P07327 |
| Molecular Weight: | 375 |
| NCBI Full Name: | alcohol dehydrogenase 1A |
| NCBI Synonym Full Names: | alcohol dehydrogenase 1A (class I), alpha polypeptide |
| NCBI Official Symbol: | ADH1A |
| NCBI Official Synonym Symbols: | ADH1 |
| NCBI Protein Information: | alcohol dehydrogenase 1A; ADH, alpha subunit; aldehyde reductase; alcohol dehydrogenase subunit alpha; alcohol dehydrogenase 1 (class I), alpha polypeptide |
| UniProt Protein Name: | Alcohol dehydrogenase 1A |
| UniProt Synonym Protein Names: | Alcohol dehydrogenase subunit alpha |
| Protein Family: | Alcohol dehydrogenase |
| UniProt Gene Name: | ADH1A |
| UniProt Entry Name: | ADH1A_HUMAN |
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