Human 4BB/TNFRSF9 Recombinant Protein (RPES1760)

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SKU:
RPES1760
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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Description

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Human 4BB/TNFRSF9 Recombinant Protein

Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells; but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9/4-1BBL; and possibly active during T cell activation.

Product Name:Human 4BB/TNFRSF9 Recombinant Protein (RPES1760)
Product Code:RPES1760
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:CD137, ILA, TNFRSF9, 4-1BB ligand receptor, CDw137, T-cell antigen 4-1BB homolog, T-cell antigen ILA
Accession:Q07011
Sequence:Leu24-Gln186
Fusion tag:C-Fc-6His
Activity:Immobilized Human 4-1BBL-His(Cat: PKSH032023) at 0.03µg/ml(100 ?l/well) can bind Human 4-1BB-Fc. The ED50 of Human 4-1BB-Fc is 7.22 ug/ml .
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human 4-1BB ligand receptor is produced by our Mammalian expression system and the target gene encoding Leu24-Gln186 is expressed with a Fc; 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:44.0 kDa
AP Mol Mass:55-75 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of PBS pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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