HOXA9 Antibody (PACO43601)
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주문- SKU:
- PACO43601
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | HOXA9 Antibody (PACO43601) |
Antibody SKU: | PACO43601 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Homeobox protein Hox-A9 protein (1-190AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO43601 at dilution of 1:100. |
![]() | Immunofluorescent analysis of PC-3 cells using PACO43601 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
![]() | Immunohistochemistry of paraffin-embedded human placenta tissue using PACO43601 at dilution of 1:100. |
Background: | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Required for induction of E-selectin and VCAM-1, on the endothelial cells surface at sites of inflammation. |
Synonyms: | Homeobox protein Hox-A9 (Homeobox protein Hox-1G), HOXA9, HOX1G |
UniProt Protein Function: | HOXA9: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Required for induction of E-selectin and VCAM-1, on the endothelial cells surface at sites of inflammation. A chromosomal aberration involving HOXA9 is found in a form of acute myeloid leukemia. Translocation t(7;11)(p15;p15) with NUP98. A chromosomal aberration involving HOXA9 may contribute to disease progression in chronic myeloid leukemia. Translocation t(7;17)(p15;q23) with MSI2. Belongs to the Abd-B homeobox family. |
UniProt Protein Details: | Protein type:DNA-binding; Oncoprotein Chromosomal Location of Human Ortholog: 7p15.2 Cellular Component: nucleoplasm; transcription factor complex; cytoplasm; nucleus Molecular Function:protein binding; enzyme binding; sequence-specific DNA binding Biological Process: embryonic forelimb morphogenesis; negative regulation of myeloid cell differentiation; transcription, DNA-dependent; multicellular organismal development; embryonic skeletal development; male gonad development; uterus development; endothelial cell activation; anterior/posterior pattern formation; regulation of transcription, DNA-dependent; mammary gland development; single fertilization; spermatogenesis; proximal/distal pattern formation |
NCBI Summary: | In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specific translocation event which causes a fusion between this gene and the NUP98 gene has been associated with myeloid leukemogenesis. Read-through transcription exists between this gene and the upstream homeobox A10 (HOXA10) gene.[provided by RefSeq, Mar 2011] |
UniProt Code: | P31269 |
NCBI GenInfo Identifier: | 6166219 |
NCBI Gene ID: | 3205 |
NCBI Accession: | P31269.4 |
UniProt Related Accession: | P31269 |
Molecular Weight: | |
NCBI Full Name: | Homeobox protein Hox-A9 |
NCBI Synonym Full Names: | homeobox A9 |
NCBI Official Symbol: | HOXA9 |
NCBI Official Synonym Symbols: | HOX1; ABD-B; HOX1G; HOX1.7 |
NCBI Protein Information: | homeobox protein Hox-A9 |
UniProt Protein Name: | Homeobox protein Hox-A9 |
UniProt Synonym Protein Names: | Homeobox protein Hox-1G |
UniProt Gene Name: | HOXA9 |
UniProt Entry Name: | HXA9_HUMAN |
Antibodies |
Anti-HOXA9 Antibody (CAB1908) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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