GUCY1A1 Antibody (PACO45874)
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주문- SKU:
- PACO45874
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | GUCY1A1 Antibody (PACO45874) |
Antibody SKU: | PACO45874 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Guanylate cyclase soluble subunit alpha-1 protein (20-152AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO45874 at dilution of 1:100. |
![]() | Immunofluorescent analysis of HepG2 cells using PACO45874 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
![]() | Immunohistochemistry of paraffin-embedded human gastric cancer using PACO45874 at dilution of 1:100. |
Background: | guanylate cyclase complex, soluble, plasma membrane, guanylate cyclase activity, receptor activity, blood circulation, cGMP biosynthetic process, nitric oxide mediated signal transduction |
Synonyms: | Guanylate cyclase soluble subunit alpha-1 (GCS-alpha-1) (EC 4.6.1.2) (Guanylate cyclase soluble subunit alpha-3) (GCS-alpha-3) (Soluble guanylate cyclase large subunit), GUCY1A1, GUC1A3 GUCSA3 GUCY1A3 |
UniProt Protein Function: | GUCY1A3: Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] |
UniProt Protein Details: | Protein type:EC 4.6.1.2; Guanylyl cyclase; Lyase; Nucleotide Metabolism - purine; Receptor, misc. Chromosomal Location of Human Ortholog: 4q32.1 Cellular Component: guanylate cyclase complex, soluble; plasma membrane Molecular Function:adenylate cyclase activity; guanylate cyclase activity; protein binding; receptor activity Biological Process: blood circulation; cGMP biosynthetic process; nitric oxide mediated signal transduction Disease: Moyamoya Disease 6 With Achalasia |
NCBI Summary: | Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] |
UniProt Code: | Q02108 |
NCBI GenInfo Identifier: | 7404351 |
NCBI Gene ID: | 2982 |
NCBI Accession: | Q02108.2 |
UniProt Secondary Accession: | Q02108,O43843, Q8TAH3, D3DP19, D6RDW3, |
UniProt Related Accession: | Q02108 |
Molecular Weight: | 77kDa |
NCBI Full Name: | Guanylate cyclase soluble subunit alpha-3 |
NCBI Synonym Full Names: | guanylate cyclase 1 soluble subunit alpha |
NCBI Official Symbol: | GUCY1A3 |
NCBI Official Synonym Symbols: | GUCA3; MYMY6; GC-SA3; GUC1A3; GUCSA3; GUCY1A1 |
NCBI Protein Information: | guanylate cyclase soluble subunit alpha-3 |
UniProt Protein Name: | Guanylate cyclase soluble subunit alpha-3 |
UniProt Synonym Protein Names: | GCS-alpha-1; Soluble guanylate cyclase large subunit |
Protein Family: | Guanylate cyclase soluble |
UniProt Gene Name: | GUCY1A3 |