GTF2B Antibody (PACO27245)
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주문- SKU:
- PACO27245
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | GTF2B Antibody (PACO27245) |
Antibody SKU: | PACO27245 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Transcription initiation factor IIB protein (1-316AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot All lanes: GTF2B antibody at 2µg/ml Lane 1: HepG2 whole cell lysate Lane 2: Hela whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/15000 dilution Predicted band size: 35 kDa Observed band size: 35 kDa . |
![]() | Immunohistochemistry of paraffin-embedded human testis tissue using PACO27245 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO27245 at dilution of 1:100. |
Background: | General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II. |
Synonyms: | Transcription initiation factor IIB (General transcription factor TFIIB) (S300-II), GTF2B, TF2B TFIIB |
UniProt Protein Function: | GTF2B: General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II. Associates with TFIID-IIA (DA complex) to form TFIID-IIA- IIB (DAB-complex) which is then recognized by polymerase II. Interacts with the transcription elongation factor TCEA2. Interacts with HIV-1 Vpr. Interacts with GPBP1. Interacts with Epstein-Barr virus EBNA2. Belongs to the TFIIB family. |
UniProt Protein Details: | Protein type:Acetyltransferase; Nuclear receptor co-regulator; Transcription factor Chromosomal Location of Human Ortholog: 1p22-p21 Cellular Component: nucleolus; nucleoplasm; nucleus Molecular Function:protein binding; thyroid hormone receptor binding; transcription factor binding Biological Process: RNA elongation from RNA polymerase II promoter; snRNA transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter |
NCBI Summary: | This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q00403 |
NCBI GenInfo Identifier: | 135629 |
NCBI Gene ID: | 2959 |
NCBI Accession: | Q00403.1 |
UniProt Secondary Accession: | Q00403,Q5JS30, A8K1A7, |
UniProt Related Accession: | Q00403 |
Molecular Weight: | 34,833 Da |
NCBI Full Name: | Transcription initiation factor IIB |
NCBI Synonym Full Names: | general transcription factor IIB |
NCBI Official Symbol: | GTF2B |
NCBI Official Synonym Symbols: | TF2B; TFIIB |
NCBI Protein Information: | transcription initiation factor IIB |
UniProt Protein Name: | Transcription initiation factor IIB |
UniProt Synonym Protein Names: | General transcription factor TFIIB; S300-II |
Protein Family: | Transcription initiation factor |
UniProt Gene Name: | GTF2B |
UniProt Entry Name: | TF2B_HUMAN |
Antibodies |
Anti-GTF2B Antibody (CAB1708) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |