GRPEL2 Antibody (PACO45545)
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주문- SKU:
- PACO45545
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | GRPEL2 Antibody (PACO45545) |
Antibody SKU: | PACO45545 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human GrpE protein homolog 2, mitochondrial protein (33-225AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human colon cancer using PACO45545 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO45545 at dilution of 1:100. |
Background: | Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70 (By similarity). |
Synonyms: | GrpE protein homolog 2, mitochondrial (Mt-GrpE#2), GRPEL2 |
UniProt Protein Function: | GRPEL2: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70. Belongs to the GrpE family. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 5q32 Cellular Component: mitochondrion; mitochondrial matrix; mitochondrial inner membrane Molecular Function:protein homodimerization activity; adenyl-nucleotide exchange factor activity; chaperone binding; unfolded protein binding Biological Process: cellular protein metabolic process; protein folding; regulation of catalytic activity; protein targeting to mitochondrion |
UniProt Code: | Q8TAA5 |
NCBI GenInfo Identifier: | 22256760 |
NCBI Gene ID: | 134266 |
NCBI Accession: | Q8TAA5.1 |
UniProt Secondary Accession: | Q8TAA5,Q49AJ6, B4DFA6, |
UniProt Related Accession: | Q8TAA5 |
Molecular Weight: | 14,277 Da |
NCBI Full Name: | GrpE protein homolog 2, mitochondrial |
NCBI Synonym Full Names: | GrpE-like 2, mitochondrial (E. coli) |
NCBI Official Symbol: | GRPEL2 |
NCBI Official Synonym Symbols: | Mt-GrpE#2 |
NCBI Protein Information: | grpE protein homolog 2, mitochondrial |
UniProt Protein Name: | GrpE protein homolog 2, mitochondrial |
UniProt Synonym Protein Names: | Mt-GrpE#2 |
Protein Family: | GrpE protein |
UniProt Gene Name: | GRPEL2 |
UniProt Entry Name: | GRPE2_HUMAN |
Antibodies |
Anti-GRPEL2 Antibody (CAB8339) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |