GPX2 Antibody (PACO51582)
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주문- SKU:
- PACO51582
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | GPX2 Antibody (PACO51582) |
Antibody SKU: | PACO51582 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Glutathione peroxidase 2 protein (71-168AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunofluorescent analysis of HepG2 cells using PACO51582 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | Could play a major role in protecting mammals from the toxicity of ingested organic hydroperoxides. Tert-butyl hydroperoxide, cumene hydroperoxide and linoleic acid, hydroperoxide but not phosphatidycholine hydroperoxide, can act as acceptors. |
Synonyms: | Glutathione peroxidase 2 (GPx-2) (GSHPx-2) (EC 1.11.1.9) (Gastrointestinal glutathione peroxidase) (Glutathione peroxidase-gastrointestinal) (GPx-GI) (GSHPx-GI) (Glutathione peroxidase-related protein 2) (GPRP-2), GPX2 |
UniProt Protein Function: | GPX2: Could play a major role in protecting mammals from the toxicity of ingested organic hydroperoxides. Tert-butyl hydroperoxide, cumene hydroperoxide and linoleic acid hydroperoxide but not phosphatidycholine hydroperoxide, can act as acceptors. Belongs to the glutathione peroxidase family. |
UniProt Protein Details: | Protein type:Other Amino Acids Metabolism - glutathione; EC 1.11.1.9; Oxidoreductase; Lipid Metabolism - arachidonic acid Chromosomal Location of Human Ortholog: 14q24.1 Cellular Component: cytoplasm; cytosol Molecular Function:electron carrier activity; glutathione peroxidase activity Biological Process: gene expression; response to reactive oxygen species; transcription initiation from RNA polymerase II promoter |
NCBI Summary: | This gene is a member of the glutathione peroxidase family and encodes a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. The protein encoded by this locus contains a selenocysteine (Sec) residue encoded by the UGA codon, which normally signals translation termination. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012] |
UniProt Code: | P18283 |
NCBI GenInfo Identifier: | 32967607 |
NCBI Gene ID: | 2877 |
NCBI Accession: | NP_002074.2 |
UniProt Secondary Accession: | P18283,Q6PJ52, Q8WWI7, Q9NRP9, |
UniProt Related Accession: | P18283 |
Molecular Weight: | 21,954 Da |
NCBI Full Name: | glutathione peroxidase 2 |
NCBI Synonym Full Names: | glutathione peroxidase 2 |
NCBI Official Symbol: | GPX2 |
NCBI Official Synonym Symbols: | GPRP; GPx-2; GI-GPx; GPRP-2; GPx-GI; GSHPx-2; GSHPX-GI |
NCBI Protein Information: | glutathione peroxidase 2 |
UniProt Protein Name: | Glutathione peroxidase 2 |
UniProt Synonym Protein Names: | Gastrointestinal glutathione peroxidase; Glutathione peroxidase-gastrointestinal; GPx-GI; GSHPx-GI; Glutathione peroxidase-related protein 2; GPRP-2 |
Protein Family: | Glutathione peroxidase |
UniProt Gene Name: | GPX2 |
UniProt Entry Name: | GPX2_HUMAN |
Antibodies | ELISA Kits |
Anti-GPX2 Antibody (CAB15999) | Human Glutathione Peroxidase 2 / GPX2 ELISA Kit |
Human Glutathione peroxidase 2 (GPX2) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |