GNPAT Antibody (PACO19726)
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주문- SKU:
- PACO19726
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | GNPAT Antibody (PACO19726) |
Antibody SKU: | PACO19726 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthetic peptide of human GNPAT |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO19726(GNPAT Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19726(GNPAT Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | This gene encodes an enzyme located in the peroxisomal membrane which is essential to the synthesis of ether phospholipids. Mutations in this gene are associated with rhizomelic chondrodysplasia punctata. |
Synonyms: | glyceronephosphate O-acyltransferase |
UniProt Protein Function: | GNPAT: Defects in GNPAT are the cause of rhizomelic chondrodysplasia punctata type 2 (RCDP2). RDCP2 is characterized by rhizomelic shortening of femur and humerus, vertebral disorders, cataract, cutaneous lesions and severe mental retardation. Belongs to the GPAT/DAPAT family. |
UniProt Protein Details: | Protein type:EC 2.3.1.42; Lipid Metabolism - glycerophospholipid; Transferase Chromosomal Location of Human Ortholog: 1q42 Cellular Component: peroxisomal membrane; peroxisomal matrix; mitochondrion; membrane; peroxisome Molecular Function:glycerone-phosphate O-acyltransferase activity; palmitoyl-CoA hydrolase activity; receptor binding Biological Process: response to drug; response to starvation; synaptogenesis; phospholipid metabolic process; glycerophospholipid biosynthetic process; cerebellum morphogenesis; phosphatidic acid biosynthetic process; cellular lipid metabolic process; response to nutrient; ether lipid biosynthetic process; paranodal junction assembly Disease: Rhizomelic Chondrodysplasia Punctata, Type 2 |
NCBI Summary: | This gene encodes an enzyme located in the peroxisomal membrane which is essential to the synthesis of ether phospholipids. Mutations in this gene are associated with rhizomelic chondrodysplasia punctata. [provided by RefSeq, Jul 2008] |
UniProt Code: | O15228 |
NCBI GenInfo Identifier: | 3913409 |
NCBI Gene ID: | 8443 |
NCBI Accession: | O15228.1 |
UniProt Secondary Accession: | O15228,Q5TBH7, Q9BWC2, B4DNM9, |
UniProt Related Accession: | O15228 |
Molecular Weight: | 680 |
NCBI Full Name: | Dihydroxyacetone phosphate acyltransferase |
NCBI Synonym Full Names: | glyceronephosphate O-acyltransferase |
NCBI Official Symbol: | GNPAT |
NCBI Official Synonym Symbols: | DAPAT; DAP-AT; DHAPAT |
NCBI Protein Information: | dihydroxyacetone phosphate acyltransferase; DHAP-AT; glycerone-phosphate O-acyltransferase; acyl-CoA:dihydroxyacetonephosphateacyltransferase |
UniProt Protein Name: | Dihydroxyacetone phosphate acyltransferase |
UniProt Synonym Protein Names: | Acyl-CoA:dihydroxyacetonephosphateacyltransferase; Glycerone-phosphate O-acyltransferase |
Protein Family: | Dihydroxyacetone phosphate acyltransferase |
UniProt Gene Name: | GNPAT |
UniProt Entry Name: | GNPAT_HUMAN |