GNG2 Antibody (PACO63311)
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주문- SKU:
- PACO63311
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | GNG2 Antibody (PACO63311) |
Antibody SKU: | PACO63311 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Peptide sequence from Human Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 protein (44-62AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | IHC image of PACO63311 diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
![]() | Immunofluorescence staining of U251 cells with PACO63311 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
![]() | IHC image of PACO63311 diluted at 1:100 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
Background: | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The β and γ chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction (By similarity). |
Synonyms: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 (G gamma-I), GNG2 |
UniProt Protein Function: | G-gamma 2: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Belongs to the G protein gamma family. |
UniProt Protein Details: | Protein type:G protein; G protein, heterotrimeric; G protein, heterotrimeric gamma Chromosomal Location of Human Ortholog: 14q22.1 Cellular Component: heterotrimeric G-protein complex; membrane; plasma membrane Molecular Function:G-protein beta-subunit binding Biological Process: dopamine receptor, adenylate cyclase activating pathway; platelet activation; protein folding; Wnt receptor signaling pathway, calcium modulating pathway |
NCBI Summary: | This gene encodes one of the gamma subunits of a guanine nucleotide-binding protein. Such proteins are involved in signaling mechanisms across membranes. Various subunits forms heterodimers which then interact with the different signal molecules. [provided by RefSeq, Aug 2011] |
UniProt Code: | P59768 |
NCBI GenInfo Identifier: | 32699499 |
NCBI Gene ID: | 54331 |
NCBI Accession: | P59768.2 |
UniProt Secondary Accession: | P59768,Q5JPE2, Q6P9A9, |
UniProt Related Accession: | P59768 |
Molecular Weight: | 8kDa |
NCBI Full Name: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 |
NCBI Synonym Full Names: | G protein subunit gamma 2 |
NCBI Official Symbol: | GNG2 |
NCBI Protein Information: | guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 |
UniProt Protein Name: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 |
UniProt Synonym Protein Names: | G gamma-I |
UniProt Gene Name: | GNG2 |
Antibodies | ELISA Kits |
Anti-GNG2 Antibody (CAB10309) | Human GNG2 (Guanine nucleotide-binding protein G (I)/G (S)/G (O) subunit gamma-2) ELISA Kit (HUFI04081) |
GNG2 Antibody (PACO09519) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |