GNB5 Antibody (PACO14440)
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주문- SKU:
- PACO14440
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | GNB5 Antibody (PACO14440) |
Antibody SKU: | PACO14440 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Fusion protein of human GNB5 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO14440(GNB5 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
![]() | Gel: 15%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human fetal brain tissue, mouse heart tissue, Primary antibody: PACO14440(GNB5 Antibody) at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 second. |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO14440(GNB5 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a γ subunit. These subunits are encoded by families of related genes. This gene encodes a β subunit. β subunits are important regulators of α subunits, as well as of certain signal transduction receptors and effectors. Alternatively spliced transcript variants encoding different isoforms exist. |
Synonyms: | guanine nucleotide binding protein (G protein), β 5 |
UniProt Protein Function: | G-beta 5: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Belongs to the WD repeat G protein beta family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:G protein, heterotrimeric beta Chromosomal Location of Human Ortholog: 15q21.2 Cellular Component: plasma membrane; nucleus Molecular Function:GTPase activity; G-protein gamma-subunit binding; signal transducer activity; protein binding; chaperone binding Biological Process: rhodopsin mediated signaling; phototransduction, visible light; regulation of rhodopsin mediated signaling; metabolic process; signal transduction |
NCBI Summary: | Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternatively spliced transcript variants encoding different isoforms exist. [provided by RefSeq, Jul 2008] |
UniProt Code: | O14775 |
NCBI GenInfo Identifier: | 38258891 |
NCBI Gene ID: | 10681 |
NCBI Accession: | O14775.2 |
UniProt Secondary Accession: | O14775,Q9HAU9, Q9UFT3, B2RBR5, |
UniProt Related Accession: | O14775 |
Molecular Weight: | 395 |
NCBI Full Name: | Guanine nucleotide-binding protein subunit beta-5 |
NCBI Synonym Full Names: | guanine nucleotide binding protein (G protein), beta 5 |
NCBI Official Symbol: | GNB5 |
NCBI Official Synonym Symbols: | GB5 |
NCBI Protein Information: | guanine nucleotide-binding protein subunit beta-5; gbeta5; transducin beta chain 5; G protein, beta-5 subunit; G protein, beta subunit 5L; guanine nucleotide-binding protein, beta subunit 5L |
UniProt Protein Name: | Guanine nucleotide-binding protein subunit beta-5 |
UniProt Synonym Protein Names: | Gbeta5; Transducin beta chain 5 |
Protein Family: | Guanine nucleotide-binding protein |
UniProt Gene Name: | GNB5 |
UniProt Entry Name: | GBB5_HUMAN |
Antibodies | ELISA Kits |
Anti-GNB5 Antibody (CAB4447) | Human GNB5 (Guanine nucleotide-binding protein subunit beta-5)ELISA Kit (HUFI04080) |
GNB5 Antibody (PACO02354) | |
GNB5 Antibody (PACO09518) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |