GNB4 Antibody (PACO51002)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO51002
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | GNB4 Antibody (PACO51002) |
Antibody SKU: | PACO51002 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Recombinant Human Guanine nucleotide-binding protein subunit beta-4 protein (105-185AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: Rat liver tissue, Mouse liver tissue, Mouse kidney tissue. All lanes: GNB4 antibody at 2µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 38 kDa. Observed band size: 38 kDa.. |
![]() | Immunohistochemistry of paraffin-embedded human colon cancer using PACO51002 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human pancreatic cancer using PACO51002 at dilution of 1:100. |
Background: | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The β and γ chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. |
Synonyms: | Guanine nucleotide-binding protein subunit beta-4 (Transducin β chain 4), GNB4 |
UniProt Protein Function: | G-beta 4: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Belongs to the WD repeat G protein beta family. |
UniProt Protein Details: | Protein type:G protein, heterotrimeric beta; G protein, heterotrimeric; Membrane protein, peripheral Chromosomal Location of Human Ortholog: 3q26.33 Cellular Component: cytosol; lysosomal membrane; plasma membrane Molecular Function:protein complex binding Biological Process: protein folding; substantia nigra development Disease: Charcot-marie-tooth Disease, Dominant Intermediate F |
NCBI Summary: | Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9HAV0 |
NCBI GenInfo Identifier: | 22256759 |
NCBI Gene ID: | 59345 |
NCBI Accession: | Q9HAV0.3 |
UniProt Secondary Accession: | Q9HAV0,B3KMH5, D3DNR8, |
UniProt Related Accession: | Q9HAV0 |
Molecular Weight: | 37,567 Da |
NCBI Full Name: | Guanine nucleotide-binding protein subunit beta-4 |
NCBI Synonym Full Names: | G protein subunit beta 4 |
NCBI Official Symbol: | GNB4 |
NCBI Official Synonym Symbols: | CMTD1F |
NCBI Protein Information: | guanine nucleotide-binding protein subunit beta-4 |
UniProt Protein Name: | Guanine nucleotide-binding protein subunit beta-4 |
UniProt Synonym Protein Names: | Transducin beta chain 4 |
Protein Family: | Guanine nucleotide-binding protein |
UniProt Gene Name: | GNB4 |
UniProt Entry Name: | GBB4_HUMAN |