GJD2 Antibody (PACO57572)
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주문- SKU:
- PACO57572
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | GJD2 Antibody (PACO57572) |
Antibody SKU: | PACO57572 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Gap junction delta-2 protein (99-197AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: U87 whole cell lysate. All lanes: GJD2 antibody at 3.2µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 37 kDa. Observed band size: 37 kDa. | |
IHC image of PACO57572 diluted at 1:500 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. | |
IHC image of PACO57572 diluted at 1:500 and staining in paraffin-embedded human lung tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
Background: | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. |
Synonyms: | Gap junction delta-2 protein (Connexin-36) (Cx36) (Gap junction alpha-9 protein), GJD2, GJA9 |
UniProt Protein Function: | GJD2: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family. Delta-type subfamily. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Cell adhesion; Membrane protein, integral; Channel, misc. Chromosomal Location of Human Ortholog: 15q14 Cellular Component: connexon complex; plasma membrane; integral to membrane Molecular Function:gap junction channel activity Biological Process: synaptic transmission; regulation of action potential; visual perception; transmembrane transport |
NCBI Summary: | This gene encodes a member of the connexin protein family. Connexins are gap junction proteins which are arranged in groups of 6 around a central pore to form a connexon, a component of the gap junction intercellular channel. The channels formed by this protein allow cationic molecule exchange between human beta cells and may function in the regulation of insulin secretion. [provided by RefSeq, Oct 2012] |
UniProt Code: | Q9UKL4 |
NCBI GenInfo Identifier: | 8928073 |
NCBI Gene ID: | 57369 |
NCBI Accession: | Q9UKL4.1 |
UniProt Secondary Accession: | Q9UKL4,O70610, O54851, Q866T7, |
UniProt Related Accession: | Q9UKL4 |
Molecular Weight: | 321 |
NCBI Full Name: | Gap junction delta-2 protein |
NCBI Synonym Full Names: | gap junction protein, delta 2, 36kDa |
NCBI Official Symbol: | GJD2 |
NCBI Official Synonym Symbols: | CX36; GJA9 |
NCBI Protein Information: | gap junction delta-2 protein; connexin 36; connexin-36; gap junction alpha-9 protein |
UniProt Protein Name: | Gap junction delta-2 protein |
UniProt Synonym Protein Names: | Connexin-36; Cx36; Gap junction alpha-9 protein |
UniProt Gene Name: | GJD2 |
UniProt Entry Name: | CXD2_HUMAN |
Antibodies |
Anti-GJD2 Antibody (CAB2883) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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