GIPC1 Antibody (PACO51546)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO51546
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | GIPC1 Antibody (PACO51546) |
Antibody SKU: | PACO51546 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human PDZ domain-containing protein GIPC1 protein (7-74AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO51546 at dilution of 1:100. |
![]() | Immunofluorescent analysis of HepG2 cells using PACO51546 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
![]() | Immunohistochemistry of paraffin-embedded human liver cancer using PACO51546 at dilution of 1:100. |
Background: | May be involved in G protein-linked signaling. |
Synonyms: | PDZ domain-containing protein GIPC1 (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (RGS19-interacting protein 1) (Synectin) (Tax interaction protein 2) (TIP-2), GIPC1, C19orf3 GIPC RGS19IP1 |
UniProt Protein Function: | GIPC1: May be involved in G protein-linked signaling. Belongs to the GIPC family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:GAP; GAP, misc.; Motility/polarity/chemotaxis; Vesicle Chromosomal Location of Human Ortholog: 19p13.12 Cellular Component: cell cortex; cytoplasm; cytoplasmic vesicle; cytosol; dendritic shaft; dendritic spine; membrane; synaptic vesicle; vesicle membrane Molecular Function:actin binding; cadherin binding; myosin binding; protein binding; protein homodimerization activity; receptor binding Biological Process: endothelial cell migration; glutamate secretion; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of cytokinesis; positive regulation of transforming growth factor beta receptor signaling pathway; protein targeting; regulation of protein stability; regulation of synaptic plasticity; synaptic transmission |
NCBI Summary: | GIPC1 is a scaffolding protein that regulates cell surface receptor expression and trafficking (Lee et al., 2008 [PubMed 18775991]).[supplied by OMIM, Apr 2009] |
UniProt Code: | O14908 |
NCBI GenInfo Identifier: | 17375873 |
NCBI Gene ID: | 10755 |
NCBI Accession: | O14908.2 |
UniProt Secondary Accession: | O14908,Q9BTC9, A8K4I3, A8MZG3, |
UniProt Related Accession: | O14908 |
Molecular Weight: | 36kDa |
NCBI Full Name: | PDZ domain-containing protein GIPC1 |
NCBI Synonym Full Names: | GIPC PDZ domain containing family member 1 |
NCBI Official Symbol: | GIPC1 |
NCBI Official Synonym Symbols: | NIP; GIPC; IIP-1; TIP-2; SEMCAP; C19orf3; Hs.6454; GLUT1CBP; RGS19IP1; SYNECTIN; SYNECTIIN |
NCBI Protein Information: | PDZ domain-containing protein GIPC1 |
UniProt Protein Name: | PDZ domain-containing protein GIPC1 |
UniProt Synonym Protein Names: | GAIP C-terminus-interacting protein; RGS-GAIP-interacting protein; RGS19-interacting protein 1; Synectin; Tax interaction protein 2; TIP-2 |
Protein Family: | PDZ domain-containing protein |
UniProt Gene Name: | GIPC1 |