GINS2 Antibody (PACO45599)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO45599
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | GINS2 Antibody (PACO45599) |
Antibody SKU: | PACO45599 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human DNA replication complex GINS protein PSF2 protein (1-185AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO45599 at dilution of 1:100. |
![]() | Immunofluorescent analysis of HepG2 cells using PACO45599 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA. |
Synonyms: | DNA replication complex GINS protein PSF2 (GINS complex subunit 2), GINS2, PSF2 |
UniProt Protein Function: | PSF2: The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single- stranded DNA. Belongs to the GINS2/PSF2 family. |
UniProt Protein Details: | Protein type:DNA replication Chromosomal Location of Human Ortholog: 16q24.1 Cellular Component: nucleoplasm Molecular Function:3'-5' DNA helicase activity; protein binding Biological Process: DNA strand elongation during DNA replication; double-strand break repair via break-induced replication |
NCBI Summary: | The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1 (GINS1; MIM 610608), Psf2, and Psf3 (GINS3; MIM 610610). The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.[supplied by OMIM, Mar 2008] |
UniProt Code: | Q9Y248 |
NCBI GenInfo Identifier: | 37999822 |
NCBI Gene ID: | 51659 |
NCBI Accession: | Q9Y248.1 |
UniProt Secondary Accession: | Q9Y248,Q6IAG9, D3DUM5, |
UniProt Related Accession: | Q9Y248 |
Molecular Weight: | 21,428 Da |
NCBI Full Name: | DNA replication complex GINS protein PSF2 |
NCBI Synonym Full Names: | GINS complex subunit 2 |
NCBI Official Symbol: | GINS2 |
NCBI Official Synonym Symbols: | PSF2; Pfs2; HSPC037 |
NCBI Protein Information: | DNA replication complex GINS protein PSF2 |
UniProt Protein Name: | DNA replication complex GINS protein PSF2 |
UniProt Synonym Protein Names: | GINS complex subunit 2 |
Protein Family: | DNA replication complex GINS protein |
UniProt Gene Name: | GINS2 |
UniProt Entry Name: | PSF2_HUMAN |