GIMAP5 Antibody (PACO23439)
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주문- SKU:
- PACO23439
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | GIMAP5 Antibody (PACO23439) |
Antibody SKU: | PACO23439 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IHC:1:50-1:100 |
Species Reactivity: | Human |
Immunogen: | Synthesized peptide derived from internal of human GIMAP5. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot analysis of extracts from HeLa cells and HT-29 cells, using GIMAP5 antibody. |
![]() | Immunohistochemistry analysis of paraffin-embedded human placenta tissue using GIMAP5 antibody. |
Background: | Required for mitochondrial integrity and T-cell survival. May contribute to T-cell quiescence By similarity. |
Synonyms: | GIMA5; GTPase; IMAP family 5; HIMAP3; IAN-5 |
UniProt Protein Function: | GIMAP5: Required for mitochondrial integrity and T-cell survival. May contribute to T-cell quiescence. Belongs to the IAN GTP-binding protein family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Hydrolase; Apoptosis; Mitochondrial; Membrane protein, integral Chromosomal Location of Human Ortholog: 7q36.1 Cellular Component: mitochondrial outer membrane; lysosome; integral to membrane Molecular Function:GTP binding |
NCBI Summary: | This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. This gene encodes an antiapoptotic protein that functions in T-cell survival. Polymorphisms in this gene are associated with systemic lupus erythematosus. Read-through transcription exists between this gene and the neighboring upstream GIMAP1 (GTPase, IMAP family member 1) gene. [provided by RefSeq, Dec 2010] |
UniProt Code: | Q96F15 |
NCBI GenInfo Identifier: | 28416949 |
NCBI Gene ID: | 55340 |
NCBI Accession: | NP_060854.2 |
UniProt Secondary Accession: | Q96F15,Q6IA75, Q96NE4, Q9NUK9, D3DWZ5, |
UniProt Related Accession: | Q96F15 |
Molecular Weight: | 34,846 Da |
NCBI Full Name: | GTPase IMAP family member 5 |
NCBI Synonym Full Names: | GTPase, IMAP family member 5 |
NCBI Official Symbol: | GIMAP5 |
NCBI Official Synonym Symbols: | IAN4; IAN5; IROD; IAN-5; IMAP3; HIMAP3; IAN4L1 |
NCBI Protein Information: | GTPase IMAP family member 5; immunity associated protein 3; immune associated nucleotide 4 like 1; immunity-associated nucleotide 5 protein; inhibitor of radiation- and OA-induced apoptosis, Irod/Ian5 |
UniProt Protein Name: | GTPase IMAP family member 5 |
UniProt Synonym Protein Names: | Immunity-associated nucleotide 4-like 1 protein; Immunity-associated nucleotide 5 protein; IAN-5; hIAN5; Immunity-associated protein 3 |
Protein Family: | GTPase IMAP family |
UniProt Gene Name: | GIMAP5 |
UniProt Entry Name: | GIMA5_HUMAN |