GFAP Antibody (PACO23011)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO23011
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | GFAP Antibody (PACO23011) |
Antibody SKU: | PACO23011 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:1000, IF:1:100-1:200 |
Species Reactivity: | Human, Rat |
Immunogen: | Peptide sequence around aa. 423~427 (E-S-K-Q-E) derived from Human GFAP. |
Form: | Liquid |
Storage Buffer: | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot analysis of extract from Rat brain, Rat hippocampus tissue and C6 cells using GFAP Antibody. |
![]() | Immunofluorescence staining of paraffin-embedded Glioma cells of Spinal Cord using GFAP Antibody. |
Background: | GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. |
Synonyms: | FLJ45472 |
UniProt Protein Function: | GFAP: a class-III intermediate filament protein. A cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. An additional transcript variant isoform has been described, but its full length sequence has not been determined. |
UniProt Protein Details: | Protein type:Cytoskeletal Chromosomal Location of Human Ortholog: 17q21 Cellular Component: membrane; cytoplasm; intermediate filament; cytosol Molecular Function:integrin binding; structural constituent of cytoskeleton; kinase binding Biological Process: Bergmann glial cell differentiation; extracellular matrix organization and biogenesis; regulation of neurotransmitter uptake; response to wounding; intermediate filament organization; neurite regeneration; astrocyte development Disease: Alexander Disease |
NCBI Summary: | This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008] |
UniProt Code: | P14136 |
NCBI GenInfo Identifier: | 121135 |
NCBI Gene ID: | 2670 |
NCBI Accession: | P14136.1 |
UniProt Secondary Accession: | P14136,Q53H98, Q5D055, Q6ZQS3, Q7Z5J6, Q7Z5J7, Q96KS4 Q96P18, Q9UFD0, B2RD44, D3DX59, E9PAX3, |
UniProt Related Accession: | P14136 |
Molecular Weight: | 432 |
NCBI Full Name: | Glial fibrillary acidic protein |
NCBI Synonym Full Names: | glial fibrillary acidic protein |
NCBI Official Symbol: | GFAP |
NCBI Protein Information: | glial fibrillary acidic protein |
UniProt Protein Name: | Glial fibrillary acidic protein |
Protein Family: | Glial fibrillary acidic protein |
UniProt Gene Name: | GFAP |
UniProt Entry Name: | GFAP_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |