GDAP1 Antibody (PACO44381)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO44381
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | GDAP1 Antibody (PACO44381) |
Antibody SKU: | PACO44381 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Ganglioside-induced differentiation-associated protein 1 protein (1-225AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: GDAP1 antibody at 1.11µg/ml + Mouse brain tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 42, 34 kDa. Observed band size: 42 kDa.. |
![]() | Immunohistochemistry of paraffin-embedded human breast cancer using PACO44381 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human liver cancer using PACO44381 at dilution of 1:100. |
Background: | Regulates the mitochondrial network by promoting mitochondrial fission. |
Synonyms: | Ganglioside-induced differentiation-associated protein 1 (GDAP1), GDAP1 |
UniProt Protein Function: | GDAP1: the ganglioside-induced differentiation associated protein-1 gene causes autosomal recessive demyelinating or axonal Charcot-Marie-Tooth neuropathy (CMT). |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 8q21.11 Cellular Component: mitochondrion; membrane; cytoplasm; nucleus; integral to mitochondrial outer membrane Biological Process: mitochondrial fission; response to retinoic acid; protein targeting to mitochondrion Disease: Charcot-marie-tooth Disease, Axonal, With Vocal Cord Paresis, Autosomal Recessive; Charcot-marie-tooth Disease, Axonal, Type 2k; Charcot-marie-tooth Disease, Type 4a; Charcot-marie-tooth Disease, Recessive Intermediate A |
NCBI Summary: | This gene encodes a member of the ganglioside-induced differentiation-associated protein family, which may play a role in a signal transduction pathway during neuronal development. Mutations in this gene have been associated with various forms of Charcot-Marie-Tooth Disease and neuropathy. Two transcript variants encoding different isoforms and a noncoding variant have been identified for this gene. [provided by RefSeq, Feb 2012] |
UniProt Code: | Q8TB36 |
NCBI GenInfo Identifier: | 269849682 |
NCBI Gene ID: | 54332 |
NCBI Accession: | Q8TB36.3 |
UniProt Secondary Accession: | Q8TB36,A8K957, E7FJF3, E7FJF4, |
UniProt Related Accession: | Q8TB36 |
Molecular Weight: | 358 |
NCBI Full Name: | Ganglioside-induced differentiation-associated protein 1 |
NCBI Synonym Full Names: | ganglioside induced differentiation associated protein 1 |
NCBI Official Symbol: | GDAP1 |
NCBI Official Synonym Symbols: | CMT4; CMT4A; CMTRIA |
NCBI Protein Information: | ganglioside-induced differentiation-associated protein 1; Charcot-Marie-Tooth neuropathy 4A; ganglioside differentiation associated protein 1 |
UniProt Protein Name: | Ganglioside-induced differentiation-associated protein 1 |
Protein Family: | Ganglioside-induced differentiation-associated protein |
UniProt Gene Name: | GDAP1 |
UniProt Entry Name: | GDAP1_HUMAN |