GDA Antibody (PACO44285)
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주문- SKU:
- PACO44285
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | GDA Antibody (PACO44285) |
Antibody SKU: | PACO44285 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Guanine deaminase protein (165-454AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: GDAantibody at 1.24µg/ml + Hela whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 52, 43, 53 kDa. Observed band size: 36 kDa.. |
![]() | Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO44285 at dilution of 1:100. |
Background: | Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. |
Synonyms: | Guanine deaminase (Guanase) (Guanine aminase) (EC 3.5.4.3) (Guanine aminohydrolase) (GAH) (p51-nedasin), GDA, KIAA1258 |
UniProt Protein Function: | GDA: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. Belongs to the ATZ/TRZ family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Nucleotide Metabolism - purine; EC 3.5.4.3; Hydrolase Chromosomal Location of Human Ortholog: 9q21.13 Cellular Component: intracellular; cytosol Molecular Function:guanine deaminase activity; zinc ion binding Biological Process: nervous system development; nucleobase, nucleoside and nucleotide metabolic process; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; purine nucleotide catabolic process; guanine catabolic process; purine base metabolic process |
NCBI Summary: | This gene encodes an enzyme responsible for the hydrolytic deamination of guanine. Studies in rat ortholog suggest this gene plays a role in microtubule assembly. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] |
UniProt Code: | Q9Y2T3 |
NCBI GenInfo Identifier: | 9910736 |
NCBI Gene ID: | 9615 |
NCBI Accession: | Q9Y2T3.1 |
UniProt Secondary Accession: | Q9Y2T3,Q5SZC7, Q9H335, Q9ULG2, B4DTY5, |
UniProt Related Accession: | Q9Y2T3 |
Molecular Weight: | 454 |
NCBI Full Name: | Guanine deaminase |
NCBI Synonym Full Names: | guanine deaminase |
NCBI Official Symbol: | GDA |
NCBI Official Synonym Symbols: | CYPIN; GUANASE; NEDASIN |
NCBI Protein Information: | guanine deaminase; GAH; p51-nedasin; guanine aminase; guanine aminohydrolase; cytoplasmic PSD95 interactor |
UniProt Protein Name: | Guanine deaminase |
UniProt Synonym Protein Names: | Guanine aminohydrolase; GAH; p51-nedasin |
UniProt Gene Name: | GDA |
UniProt Entry Name: | GUAD_HUMAN |